Borisov 2021 Antioxidants (Basel)
Borisov VB, Siletsky SA, Nastasi MR, Forte E (2021) ROS defense systems and terminal oxidases in bacteria. Antioxidants (Basel) 10:839. |
Borisov Vitaliy B, Siletsky Sergey A, Nastasi Martina R, Forte Elena (2021) Antioxidants (Basel)
Abstract: Reactive oxygen species (ROS) comprise the superoxide anion (O2β’-), hydrogen peroxide (H2O2), hydroxyl radical (β’OH), and singlet oxygen (1O2). ROS can damage a variety of macromolecules, including DNA, RNA, proteins, and lipids, and compromise cell viability. To prevent or reduce ROS-induced oxidative stress, bacteria utilize different ROS defense mechanisms, of which ROS scavenging enzymes, such as superoxide dismutases, catalases, and peroxidases, are the best characterized. Recently, evidence has been accumulating that some of the terminal oxidases in bacterial respiratory chains may also play a protective role against ROS. The present review covers this role of terminal oxidases in light of recent findings. β’ Keywords: Bacteria, Oxidative stress, Reactive oxygen species, Redox enzymes, Terminal oxidases β’ Bioblast editor: Reiswig R β’ O2k-Network Lab: IT Rome Sarti P
Labels: MiParea: Respiration
HRR: Oxygraph-2k
2021-08