Hydroxycinnamate

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Hydroxycinnamate

Description

Hydroxycinnamate (alpha-cyano-4-hydroxycinnamic acid) is an inhibitor of the pyruvate carrier (0.65 mM). Above 10 mM pyruvate, hydroxycinnamate cannot inhibit respiration from pyruvate, since the weak pyruvic acid can pass the inner mt-membrane in non-dissociated form.

Abbreviation: Hci

Reference: Gnaiger 2012 MitoPathways



MitoPedia topics: Inhibitor