Lenaz Giorgio

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Lenaz Giorgio

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1

Name	Lenaz Giorgio, Prof. Dr.
Institution	Department of Biochemistry "G. Moruzzi", University of Bologna, IT
Address	Dipartimento di Biochimica "G. Moruzzi," Via Irnerio 48, 40126 Bologna Italy,
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Email	[email protected]
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O2k-Network Lab	IT Bologna Genova ML

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Publications

	Published	Reference
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Lenaz 2017 Royal Society of Chemistry Publishing, London, UK	2017	Lenaz G, Tioli G, Falasca AI, Genova ML (2017) Respiratory supercomplexes in mitochondria. In: Mechanisms of primary energy trasduction in biology. M Wikstrom (ed). Royal Society of Chemistry Publishing, London, UK 296-337.
Enriquez 2014 Mol Syndromol	2014	Enriquez JA, Lenaz G (2014) Coenzyme Q and the respiratory chain: coenzyme Q pool and mitochondrial supercomplexes. Mol Syndromol 5:119-40.
Lenaz 2010 Biochim Biophys Acta	2010	Lenaz G, Baracca A, Barbero G, Bergamini C, Dalmonte ME, Del Sole M, Faccioli M, Falasca A, Fato R, Genova ML, Sgarbi G, Solaini G (2010) Mitochondrial respiratory chain super-complex I-III in physiology and pathology. Biochim Biophys Acta 797(6-7):633-40.
Dalmonte 2009 J Biol Chem	2009	Dalmonte ME, Forte E, Genova ML, Giuffrè A, Sarti P, Lenaz G (2009) Control of respiration by cytochrome c oxidase in intact cells: role of the membrane potential. J Biol Chem 284:32331-5.
Lenaz 2009 Int J Biochem Cell Biol	2009	Lenaz G, Genova ML (2009) Structural and functional organization of the mitochondrial respiratory chain: A dynamic super-assembly. Int J Biochem Cell Biol 41:1750-72.
Fato 2009 Biochim Biophys Acta	2009	Fato R, Bergamini C, Bortolus M, Maniero AL, Leoni S, Ohnishi T, Lenaz G (2009 ) Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species. Biochim Biophys Acta 1787(5):384-92.
Rauchova 2008 J Bioenerg Biomembr	2008	Rauchova H, Drahota Z, Bergamini C, Fato R, Lenaz G (2008) Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone). J Bioenerg Biomembr 40:85-93.
Lenaz 2007 Am J Physiol Cell Physiol	2007	Lenaz G, Genova ML (2007) Kinetics of integrated electron transfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling. Am J Physiol Cell Physiol 292:C1221-39. doi: 10.1152/ajpcell.00263.2006.
Rauchova 2005 Biochem Biophys Res Comm	2005	Rauchova H, Vrbacky M, Bergamini C, Fato R, Lenaz G, Houstek J, Drahota Z (2005) Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone. Biochem Biophys Res Comm 339:362-6.
Bianchi 2004 J Biol Chem	2004	Bianchi C, Genova ML, Parenti Castelli G, Lenaz G (2004) The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis. J Biol Chem 279:36562-9.
Rauchova 2003 Acta Biochim Polonica	2003	Rauchova H, Drahota Z, Rauch P, Fato R, Lenaz G (2003) Coenzyme Q releases the inhibitory effect of free fatty acids on mitochondrial glycerophosphate dehydrogenase. Acta Biochim Polonica 50:405-13.
Rauchova 2003 Acta Biochim Pol	2003	Rauchová H, Drahota Z, Rauch P, Fato R, Lenaz G (2003) Coenzyme Q releases the inhibitory effect of free fatty acids on mitochondrial glycerophosphate dehydrogenase. Acta Biochim Pol 50:405-13.
Bianchi 2003 Biofactors	2003	Bianchi C, Fato R, Genova ML, Parenti Castelli F, Lenaz G (2003) Structural and functional organization of Complex I in the mitochondrial respiratory chain. Biofactors 18:3-9.
Pich 2002 Free Radic Res	2002	Pich MM, Castagnoli A, Biondi A, Bernacchia A, Tazzari PL, D'Aurelio M, Castelli GP, Formiggini G, Conte R, Bovina C, Lenaz G (2002) Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress. Free Radic Res 36:429-36.
Drahota 2002 J Bioenerg Biomembr	2002	Drahota Z, Chowdhury SK, Floryk D, Mrácek T, Wilhelm J, Rauchova H, Lenaz G, Houstek J (2002) Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide. J Bioenerg Biomembr 34:105-13.
Rauchova 1997 Arch Biochem Biophys	1997	Rauchová H, Fato R, Drahota Z, Lenaz G (1997) Steady-state kinetics of reduction of coenzyme Q analogs by glycerol-3-phosphate dehydrogenase in brown adipose tissue mitochondria. Arch Biochem Biophys 344:235-41.
Rauchova 1995 Physiol Res	1995	Rauchová H, Drahota Z, Lenaz G (1995) Function of coenzyme Q in the cell: some biochemical and physiological properties. Physiol Res 44:209-16.
Estornell 1992 FEBS Letters	1992	Estornell E, Fato R, Castelluccio C, Cavazzoni M, Parenti Castelli G, Lenaz G (1992) Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria. FEBS Letters 311:107-9.
Lenaz 1988 J Membr Biol	1988	Lenaz G (1988) Role of mobility of redox components in the inner mitochondrial membrane. J Membr Biol 104:193-209.

Abstracts

	Published	Reference
Tioli 2019 MiP2019	2019	Involvement of mitochondrial respiratory supercomplexes in anti-bacterial innate immunity.
Genova 2018 MiP2018	2018	Respiratory supercomplexes: evidence for separate though interconnected compartments of Coenzyme Q₁₀ in mammalian mitochondria.