MiPschool Greenville 2015

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MiPschool Greenville 2015

Publications in the MiPMap

Greenville NC US, 2015 Aug 10-14. 9th MiPschool for cellular bioenergetics and mitochondrial physiology students.

Β» http://www.ecu.edu/cs-dhs/ecdoi/Home-9th-Mitochondrial-Physiology-School-Greenville-NC.cfm

Mitochondrial Physiology Society (2015-08-10) MitoGlobal

Abstract: 9th MiPschool for cellular bioenergetics and mitochondrial physiology students, 2015 Aug 10-14, Greenville, US.

Β» Global conference highlights mitochondria expertise at ECU, by Kathryn Kennedy ECU News Services.


ORO, 2015 

Location: Greenville, North Carolina, USA

Date: August 10-14, 2015

Local organizers: P Darrell Neufer (Email: [email protected]), David A Brown (Email: [email protected] and Ashley Busada (Email: [email protected]) East Carolina University, NC, US, The MiPsociety.

Venue: East Carolina University, East Carolina Heart Institute, Greenville, North Carolina, USA

Number of participants: Max. 75 participants


East Carolina Heart Institute

All sessions were held in the conference facilities at the East Carolina Heart Institute on the health sciences campus of East Carolina University.

Β» East Carolina University, East Carolina Diabetes & Obesity Institute, East Carolina Heart Institute, Greenville, NC, USA


  • I really enjoyed the MiP in NC this past month. - David H. Jang, National Heart, Lung, and Blood Institute (NHLBI) K12 Scholar, University of Pennsylvania, Perelman School of Medicine Department of Emergency Medicine, Philadelphia, PA, USA (2015-08-25).
  • I really enjoyed the MiPschool, I believe it was one of the most useful meetings for me and I hope I can attend at more mitochondrial meetings. - Ibolya Rutkai, Tulane Univ School Med, Dept Pharmacology, New Orleans, LA, USA (2015-08-25).
  • I would like to say "THANK YOU" to all the people who make the MiPschool Greenville 2015 so successful! I greatly enjoyed my time at the MiPschool and, importantly, learned a lot at the school. - Peng Zhang (2015-08-21).
  • Congratulations to a nice summer school. - Mingyao Liu, Institute of Medical Science, Faculty of Medicine, University of Toronto, Ontario, Canada (2015-08-21).
  • A great summer school. Tremendous organization and all came off with great care. Also fantastic opportunities to interact and exchange ideas. Congratulations. Coupled with the workshops made a very good week. - Charles Hoppel, O2k-Network Lab: US OH Cleveland Hoppel CL (2015-08-20).
  • Thanks for last week. Your presence and insights were appreciated throughout the meeting. - Jacques Robidoux (2015-08-20)
  • The MiPevent held in Greenville was indeed a great learning and networking experience. - Naeem K Patil, Vanderbilt University Medical Center, Nashville, TN, USA (2015-08-20).
  • Thanks for a great meeting! - Rachel Gioscia-Ryan, Colorado, USA (2015-08-20).
  • Thank you for your email and for the program put on at the MiP School in Greenville, NC. Liam F Fitzgerald, Muscle Physiology Laboratory, Department of Kinesiology, University of Massachusetts, Amherst, USA (2015-08-19).
  • Great Meeting! - Gene Kelly, Sr. Director, Commercial & Scientific Liaison, STEALTH BIOTHERAPEUTICS, Newton, MA, USA (2015-08-19).

David H. Jang, MD, MSc National Heart, Lung, and Blood Institute (NHLBI) K12 Scholar University of Pennsylvania Perelman School of Medicine Department of Emergency Medicine

The Center for Mitochondrial/Epigenomic Medicine and The Center for Resuscitation Science Colket Translational Research Building 3501 Civic Center Boulevard, Suite 6200 Philadelphia, PA 19104-4399

Some impressions

Abstracts - alphabetical order

Bernhardt 2015 Abstract MiPschool Greenville 2015Regulation of Ca2+ entry during oocyte maturation and following fertilization.Poster
Bhattarai 2015 Abstract MiPschool Greenville 2015Exercise improves whole-body and skeletal muscle oxidative capacity in burned children.Poster
Broughton 2015 Abstract MiPschool Greenville 2015Natural selection on OXPHOS proteins varies among organisms with differences in aerobic performance.Poster
Cortright 2015 Abstract MiPschool Greenville 2015Intramyocellular triacylglycerol is associated with peroxisomal biogenesis in skeletal muscle from lean and obese humans.
Doerrier 2015 Abstract MiPschool Greenville 2015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.Oral
Funk 2015 Abstract MiPschool Greenville 2015Isolated mitochondria from liver and brain of long-lived growth hormone receptor gene disrupted mice demonstrate reduced respiration rates.Oral
George 2015 Abstract MiPschool Greenville 2015Mitochondria do not directly oxidize lactate within the cerebral cortex or hippocampus.Poster
Gioscia-Ryan 2015 Abstract MiPschool Greenville 2015Voluntary aerobic exercise increases stress resilience and improves mitochondrial health in arteries of old mice.Oral
Gudiksen 2015 Abstract MiPschool Greenville 2015IL-6 modulates regulation of PDH during acute prolonged exercise.Poster
Huang 2015 Abstract MiPschool Greenville 2015Intramyocellular triacylglycerol is associated with peroxisomal biogenesis in skeletal muscle from lean and obese humans.Oral
Hyunhee 2015 Abstract MiPschool Greenville 2015Hypothermic ischemia-normothermic reperfusion-induced necrotic cell death and mitochondrial dysfunction in lung epithelial cells are mediated by RIPK and calpain.Poster
Kirkman 2015 Abstract MiPschool Greenville 2015Mitochondria derived reactive oxygen species and microvascular dysfunction in chronic kidney disease.Poster
Kolb 2015 Abstract MiPschool Greenville 2015Hydrodynamic delivery for the treatment of acute kidney injury.Poster
Laner 2015 Abstract MiPschool Greenville 2015Comparative mitochondrial physiology: OXPHOS and ET capacity in permeabilized fibers of canine superathletes.Oral
Mahdaviani 2015 Abstract MiPschool Greenville 2015Lipid droplets interact with an exclusive sub-population of mitochondria in brown adipocyte.Poster
Makhnyeva 2015 Abstract MiPschool Greenville 2015Effect of cGMP-dependent protein kinase (PKG) signaling on mitochondrial content in Drosophila melanogaster subjected to anoxia and reoxygenation.Poster
Matarne 2015 Abstract MiPschool Greenville 2015Chronic activation of AMP-activated protein kinase increases oxidative capacity and monocarboxylate transporter expression in skeletal muscle of pigs.Poster
Morris 2015 Abstract MiPschool Greenville 2015Intrinsic high aerobic capacity is associated with protection of mitochondrial respiratory capacity and decreased inflammation following chronic high-fat/high-cholesterol diet challenge.Poster
Patil 2015 Abstract MiPschool Greenville 2015Impaired adaptive immune system function following burn wound infection and evaluation of anti-PD-L1 antibody as an immunotherapeutic agent.Poster
Rutkai 2015 Abstract MiPschool Greenville 2015Sex-differences in mitochondrial respiration is mediated by nitric oxide in rat cerebral arteries.Oral
Schmidt 2015 Abstract MiPschool Greenville 2015High-fat diet induced mitochondrial dysfunction exacerbates limb pathology in genetically ischemia protected mice.Poster
Sheldon 2015 Abstract MiPschool Greenville 2015eNOS is required to preserve hepatic mitochondrial function in western diet-induced nonalcoholic fatty liver disease.Oral
Sullivan 2015 Abstract MiPschool Greenville 2015Lipid microdomains containing supercomplexes are enriched with multiple phospholipids including cardiolipin: A detergent extraction study.Poster
Template 2015 Abstract MiPschool Greenville 2015
Terence 2015 Abstract MiPschool Greenville 2015Mitochondrial dysfunction is a genetic component of ischemic tissue pathology and occurs independent of differential blood flow in the murine limb.Poster
Tyrrell 2015 Abstract MiPschool Greenville 2015Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults.Oral
Zhang 2015 Abstract MiPschool Greenville 2015Skeletal muscle NAMPT overexpression prevents mitochondrial dysfunction during hindlimb unloading induced muscle atrophy.Poster

Β» MiPschool Greenville 2015 Abstracts in the MiPMap - sort by MiPareas, species, tissues, respiratory states, diseases, ...*

As a satellite event prior to the MiPschool Greenville, an OROBOROS O2k-Workshop took place on high-resolution respirometry and O2k-Fluorometry: IOC Greenville

Recommended reading

  • Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. OROBOROS MiPNet Publications, Innsbruck:80 pp. - Β»Bioblast linkΒ«
A hard copy of this monograph on mitochondrial physiology is included in the MiPschool material. It is available on-line free of charge and provides a background on OXPHOS analysis: From oxygen concentration to oxygen flux β€’β€’ Membrane potential: electric and chemical forces β€’β€’ Coupling and efficiency β€’β€’ Biochemical thresholds β€’β€’ Respiratory states β€’β€’ MitoPathways to electron transfer complexes β€’β€’ Normalization of mitochondrial respiration: coupling control and substrate control.

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