Molina 2022 Abstract Bioblast

3.2. «10+5» Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina Anthony JA (2022) Platelet bioenergetics are associated with resting metabolic rate and exercise capacity in older women. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Bioenergetics Communications«

Link: Bioblast 2022: BEC Inaugural Conference

Heimler Stephanie R, Phang Howard J, Bergstrom Jaclyn, Mahapatra Gargi, Dozier Stephen, Gnaiger Erich, Molina Anthony JA (2022)

Event: Bioblast 2022

This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in women over 60 years of age. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.

• Keywords: platelets, resting metabolic rate RMR, cardiopulmonary exercise testing, OXPHOS capacity P, electron transfer capacity E, inverted regression analysis

• O2k-Network Lab: AT Innsbruck Oroboros, US CA San Diego Molina AJA, US NC Winston-Salem Molina AJA

Affiliations

Heimler SR¹, Phang HJ¹, Bergstrom J¹, Mahapatra G², Dozier S¹, Gnaiger E³, Molina AJA¹

Division of Geriatrics, Gerontology, and Palliative Care; Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA - [email protected]
Section on Gerontology and Geriatrics, Sticht Center for Healthy Aging and Alzheimer's Prevention, Department of Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA
Oroboros Instruments, Innsbruck, Austria

Figures

Graphical abstract

List of abbreviations, terms and definitions - MitoPedia

» MitoPedia: Terms and abbreviations

Labels: MiParea: Respiration, Exercise physiology;nutrition;life style

Organism: Human Tissue;cell: Blood cells Preparation: Permeabilized cells

Coupling state: OXPHOS, ET Pathway: F, N, S, Gp, ROX HRR: Oxygraph-2k Event: A3