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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (356 entries) 356 498 2 Exercise physiology;nutrition;life style 692 964 3 Comparative MiP;environmental MiP 306 451 4 Pharmacology;toxicology 775 927 5 mt-Biogenesis;mt-density 243 325 6 Genetic knockout;overexpression 575 641 7 Instruments;methods 246 378
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 246 381 2 Alzheimer's 65 89 3 Autism 6 10 4 Cancer 321 429 5 Cardiovascular 177 246 6 COPD 9 12 7 Diabetes 326 428 8 Inherited 61 91 9 Infectious 43 60 10 Myopathy 60 71 11 Neurodegenerative 155 216 12 Obesity 225 367 13 Parkinson's 57 93 14 Sepsis 69 79 15 Other 250 321
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 92 152 2 Cryopreservation 38 61 3 Hypoxia 91 179 4 Ischemia-reperfusion 305 409 5 Oxidative stress;RONS 551 779 6 Permeability transition 69 90 7 Temperature: hypothermia; hyperthermia 90 110
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 6 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 56 73 4 Caenorhabditis elegans (» Nematodes) 22 30 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 59 83 7 Comparative MiP 306 451
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 22 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 12 17 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 106 141 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 22 39 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 18 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 50 61 12 Plants 30 55 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 36 51 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 42 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 163 227 2 Genital 87 118 3 Heart 663 859 4 Kidney 130 161 5 Liver 588 762 6 Lung;Gill 53 72 7 Nervous system 558 673 8 Skeletal muscle 1003 1245
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 229 284 2 Endothelial;epithelial;mesothelial cell 236 269 3 Fibroblast 191 250 4 Islet cell;pancreas;thymus 47 59 5 Leukemia 22 25 6 Lymphocyte 54 71 7 Platelets 110 128 8 Stem cells 35 47
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 15 2 HEK 79 99 3 HeLa 35 52 4 Neuroblastoma 36 41 5 HUVEC 19 22 6 Macrophage-derived cell lines 25 34 7 Other cells and cell lines 281 323
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 48 237 2 Intact organ 22 36 3 Living cells 1046 1173 4 Permeabilized cells 630 663 5 Permeabilized tissue 1012 1098 6 Homogenate 328 366 7 Isolated mitochondria 1160 1447 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 2 10 10 Enzyme 39 74 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 25 2 Complex I CI 444 532 3 Complex II;succinate dehydrogenase CII 392 464 4 Complex III CIII 297 346 5 Complex IV;cytochrome c oxidase CIV 402 473 6 Complex V;ATP synthase CV 218 258 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 55 77 9 Supercomplex 44 60 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 77 100 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 146 193 2 ATP production 75 112 3 Aerobic glycolysis 44 85 4 Amino acid 9 19 5 Calcium 97 163 6 Coupling efficiency;uncoupling 80 145 7 Cyt c Cytochrome c 40 53 8 Fatty acid FA substrate kinetics 120 144 9 Flux control 52 82 10 Inhibitor Inhibitor kinetics 127 158 11 Ion;substrate transport 56 103 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
103 157 13 Oxygen kinetics 100 138 14 Q-junction effect 13 55 15 Redox state 48 83 16 Substrate Fuel substrate kinetics 178 230 17 Temperature Temperature dependence 66 91 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 53 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2574 2782 2 R 
ROUTINE respiration
Physiological state, living cells 796 876 3 E 
ET capacity
Maximal noncoupled respiration 1825 1923 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2281 2425
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 537 636 2 N N-pathway control state NADH-linked, level 4 2194 2333 3 S S-pathway control state Succinate-linked, level 3 1493 1575 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 138 160 5 DQ Duorquinol-linked, level 2 23 27 6 CIV Complex IV single step Ascorbate & TMPD, level 1 617 644 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1377 1430 8 Other 128 144 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1309 1359
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1003 1245 2 O2k-Publications: Human heart 663 859 3 O2k-Publications: Skeletal muscle - human vs mouse 36 45
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35