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Proton slip

From Bioblast


high-resolution terminology - matching measurements at high-resolution


Proton slip

Description

Proton slip is a property of the proton pumps (Complexes CI, CIII, and CIV) when the proton slips back to the matrix side within the proton pumping process. Slip is different from the proton leak, which depends on ฮ”p and is a property of the inner mt-membrane (including the boundaries between membrane-spanning proteins and the lipid phase). Slip is an uncoupling process that depends mainly on flux and contributes to a reduction in the biochemical coupling efficiency of ATP production and oxygen consumption. Together with proton leak and cation cycling, proton slip is compensated for by LEAK respiration or LEAK oxygen flux, L. Compare: Proton leak.


Reference: BEC 2020.1, Gnaiger 2020 BEC MitoPathways


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Bioblast links: Uncoupling - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
Specific
ยป Artefacts by single dose uncoupling
ยป ATP synthase
ยป CCCP
ยป Coupling-control protocol
ยป DNP
ยป Dyscoupled respiration
ยป FCCP
ยป Is respiration uncoupled - noncoupled - dyscoupled?
ยป Noncoupled respiration: Discussion
ยป Uncoupler
ยป Uncoupled respiration - see ยป Noncoupled respiration
ยป Uncoupling proteins
ยป Uncoupling protein 1
ยป Uncoupler titrations - Optimum uncoupler concentration
Respiratory states and control ratios
ยป Biochemical coupling efficiency
ยป Coupling-control state
ยป Electron-transfer-pathway state
ยป Electron-transfer pathway
E.jpg ET capacity
ยป E-L coupling efficiency
ยป Flux control efficiency
ยป Flux control ratio
ยป LEAK-control ratio
ยป LEAK respiration
ยป Noncoupled respiration
ยป OXPHOS
ยป OXPHOS capacity; ยป State 3
ยป OXPHOS-control ratio, P/E ratio
ยป Respiratory acceptor control ratio
ยป ROUTINE-control ratio
ยป ROUTINE respiration
ยป ROUTINE state
ยป State 3u
ยป State 4
ยป Uncoupling-control ratio UCR
General (alphabetical order)
ยป Adenine nucleotide translocase
ยป Adenylates
ยป Electron transfer pathway
ยป Mitochondrial preparations
ยป mt-membrane potential
ยป Oxygen flux
ยป Phosphorylation system
ยป Proton leak
ยป Proton slip
ยป TIP2k
Other keyword lists
ยป Template:Keywords: Force and membrane potential



Questions.jpg


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Bioblast links: pH and protons - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
pH and protons
ยป pH
ยป hydrogen ion H+
ยป hydron H+
ยป hydronium ion H3O+
ยป hydride H-
ยป proton p+
ยป pH buffering capacity
ยป proton flux
ยป proton pump versus hydrogen ion pump
ยป proton leak
ยป proton slip
ยป protonmotive force
O2k-pH
ยป O2k-Catalogue: O2k-pH ISE-Module
ยป O2k-Manual pH electrode: MiPNet23.15 O2k-pH ISE-Module
ยป O2k-SOP: MiPNet08.16 pH calibration
ยป File:PH-Calibration-List.xls
ยป NextGen-O2k, ratiometric: Carboxy SNARF 1
ยป NextGen-O2k, ratiometric: HPTS
ยป pH calibration buffers
O2k-Publications
ยป O2k-Publications: O2k-pH ISE-Module
HRFR - general
ยป O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
ยป O2k signals and output
ยป O2k-SOP: MiPNet14.06 Instrumental O2 background
ยป MiPNet19.18A O2k-Series G: Start
ยป ESD
ยป O2k configuration
ยป O2k control
ยป O2k-FluoRespirometer
ยป O2k-Main Unit#O2k-Series
ยป Titration-Injection microPump
ยป Compare: O2k-TPP+_ISE-Module
DatLab
ยป DatLab 7
ยป MiPNet26.06 DatLab 7: Guide
ยป DatLab 6
ยป MiPNet19.18C DatLab 6: Guide
ยป MiPNet19.18D O2k-Series G and DatLab 6: Calibration
ยป Reference layouts for DatLab graphs



MitoPedia methods: Respirometry 


MitoPedia topics: Uncoupler