From Bioblast
Description
Pyruvate dehydrogenase is the first component enzyme of the pyruvate dehydrogenase complex, which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle.
Abbreviation: PDH
Reference: Gnaiger 2020 BEC MitoPathways, Hildyard 2003 Biochem J
MitoPedia topics:
Enzyme