Sparks Lauren M

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Sparks Lauren M

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1

Name	Sparks Lauren M, PhD
Institution	Translational Research Institute for Metabolism and Diabetes, US
Address	301 East Princeton Street 6400 Sanger Road, and Adjunct Assistant Professor Diabetes and Obesity Research Center Sanford Burnham Prebys Medical Discovery Institute (SBP), Lake Nona 6400 Sanger Road, FL-32827, 32804
City	Orlando
State/Province	Florida (FL)
Country	USA
Email	[email protected]
Weblink	http://www.tri-md.org/about-us/team-members/lauren-m-sparks-phd
O2k-Network Lab	NL Maastricht Schrauwen P, US FL Orlando Sparks LM

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Topics: Muscle mitochondria, fatty acids, human adipocytes and myotubes

Publications

	Published	Reference
Whytock 2023 Am J Physiol Endocrinol Metab	2023	Whytock KL, Pino MF, Sun Y, Yu G, De Carvalho FG, Yeo RX, Vega RB, Parmar G, Divoux A, Kapoor N, Yi F, Cornnell H, Patten DA, Harper ME, Gardell SJ, Smith SR, Walsh MJ, Sparks LM (2023) Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity. https://doi.org/10.1152/ajpendo.00143.2023
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Vega 2020 Physiol Rep	2020	Vega RB, Brouwers B, Parsons SA, Stephens NA, Pino MF, Hodges A, Yi F, Yu G, Pratley RE, Smith SR, Sparks LM (2020) An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression. Physiol Rep 8:e14416.
Pino 2019 Physiol Genomics	2019	Pino MF, Stephens NA, Eroshkin AM, Yi F, Hodges A, Cornnell HH, Pratley RE, Smith SR, Wang M, Han X, Coen PM, Goodpaster BH, Sparks LM (2019) Endurance training remodels skeletal muscle phospholipid composition and increases intrinsic mitochondrial respiration in men with type 2 diabetes. Physiol Genomics 51:586-95.
Brouwers 2018 Front Physiol	2018	Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR (2018) Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training. Front Physiol 9:704.
Pino 2017 Int J Obes (Lond)	2017	Pino MF, Divoux A, Simmonds AV, Smith SR, Sparks LM (2017) Investigating the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53.
Sparks 2016 Diabetologia	2016	Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9.
Van de Weijer 2015 Diabetes	2015	van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD⁺ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201.
Vijgen 2013 J Clin Endocrinol Metab	2013	Vijgen GH, Sparks LM, Bouvy ND, Schaart G, Hoeks J, van Marken Lichtenbelt WD, Schrauwen P (2013) Increased oxygen consumption in human adipose tissue from the "brown adipose tissue" region. J Clin Endocrinol Metab 98:E1230-4.
Bosma 2012 Histochem Cell Biol	2012	Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK (2012) The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria. Histochem Cell Biol 137:205-16.
Phielix 2012 Diabetes	2012	Phielix E, Meex R, Ouwens DM, Sparks LM, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance. Diabetes 61:2472-8.
Wu 2012 Cell	2012	Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang AH, Khandekar M, Virtanen KA, Nuutila P, Schaart G, Huang K, Tu H, van Marken Lichtenbelt WD, Hoeks J, Enerbäck S, Schrauwen P, Spiegelman BM (2012) Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell 150:366-76.

Abstracts

	Published	Reference
Pino 2023 Abstract IOC162	2023	Pino MF, Kapar SG, Laurent NL, Erickson ML, Sparks LM (2023) Characterization of human subcutaneous adipose-derived stem cells isolated from healthy young and old individual. Mitochondr Physiol Network 28.02
Sparks 2014 Abstract MiP2014	2014	NAMPT remodels substrate metabolism in skeletal muscle.

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