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Template:SUIT-006 O2 mt D022

From Bioblast
MitoPedia: SUIT

Steps and respiratory states

1SRot;2D;2c;3(Omy);4U;5Ama.png

Step State Pathway Q-junction Comment - Events (E) and Marks (M)
1SRot SL S CII 1SRot
2D SP S CII 1SRot;2D
2c ScP S CII 1SRot;2D;2c
(3Omy) ScL(Omy) 1SRot;2D;2c;(3Omy)
  • Omy addition is skipped in SUIT-006 O2 mt D022
  • Succinate, S ( type S-pathway to Q).
  • Non-phosphorylating resting state (LEAK state); LEAK-respiration, L(Omy), after blocking the ATP synthase with oligomycin.
4U SE S CII 1SRot;2D;2c;4U
5Ama ROX 1SRot;2D;2c;4U;5Ama
  • Rox is the residual oxygen consumption in the ROX state, due to oxidative side reactions, estimated after addition of antimycin A (inhibitor of CIII). Rox is subtracted from oxygen flux as a baseline for all respiratory states, to obtain mitochondrial respiration (mt).


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