From Bioblast
US IA Iowa City Anderson EJ
| O2k-Network Lab | College of Pharmacy,
University of Iowa Power-O2k Network Cluster: US IA Iowa City University of Iowa |
|---|---|
| Address | 180 S. Grand Ave., 52242 |
| City | Iowa City |
| State/Prov | Iowa (IA) |
| Country | USA |
| Weblink | |
| Contact | Anderson Ethan J |
| Team | |
| Team previous | |
| Status | 2 Power-O2k 2009- |
| Oroboros Events | IOC44 |
| Topics | obesity, insulin resistance, exercise, fat oxidation, skeletal muscle |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Stein 2018 Cell Rep | 2018 | Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20. |
| Nelson 2018 Amino Acids | 2018 | Nelson MM, Builta ZJ, Monroe TB, Doorn JA, Anderson EJ (2018) Biochemical characterization of the catecholaldehyde reactivity of L-carnosine and its therapeutic potential in human myocardium. Amino Acids 51:97-102. |
| Pereira 2017 EMBO J | 2017 | Pereira RO, Tadinada SM, Zasadny FM, Oliveira KJ, Pires KMP, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED (2017) OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J 36:2126-45. |
| Darrell 2017 US Patent | 2017 | Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1. |
| Lark 2016 Am J Physiol Cell Physiol | 2016 | Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45. |
| Katunga 2015 Mol Metab | 2015 | Katunga LA, Gudimella P, Efird JT, Abernathy S, Mattox TA, Beatty C, Darden TM, Thayne KA, Alwair H, Kypson AP, Virag JA, Anderson EJ (2015) Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. Mol Metab 4:493-506. |
| Grevengoed 2015 J Lipid Res | 2015 | Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82. |
| Kwak 2012 Free Radic Biol Med | 2012 | Kwak HB, Thalacker-Mercer A, Anderson EJ, Lin CT, Kane DA, Lee NS, Cortright RN, Bamman MM, Neufer PD (2012) Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes. Free Radic Biol Med 52:198-207. |
| Anderson 2011 Am J Physiol Heart Circ Physiol | 2011 | Anderson EJ, Rodriguez E, Anderson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways. Am J Physiol Heart Circ Physiol 300:H118-24. |
| Kane 2011 Am J Physiol Endocrinol Metab | 2011 | Kane DA, Lin CT, Anderson EJ, Kwak HB, Cox JH, Brophy PM, Hickner RC, Neufer PD, Cortright RN (2011) Progesterone increases skeletal muscle mitochondrial H2O2 emission in non-menopausal women. Am J Physiol Endocrinol Metab 300:E528-35. |
| Perry 2011 Biochem J | 2011 | Perry CG, Kane DA, Lin CT, Kozy R, Cathey BL, Lark DS, Kane CL, Brophy PM, Gavin TP, Anderson EJ, Neufer PD (2011) Inhibiting myosin-ATPase reveals a dynamic range of mitochondrial respiratory control in skeletal muscle. Biochem J 437:215-22. |
| Boyle 2011 Int J Obes | 2011 | Boyle KE, Zheng D, Anderson EJ, Neufer PD, Houmard JA (2011) Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans. Int J Obes 36:1025-31. |
| Kane 2010 Free Radic Biol Med | 2010 | Kane DA, Anderson EJ, Price III JW, Woodlief TL, Lin C-T, Bikman BT, Cortright RN, Neufer PD (2010) Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats. Free Radic Biol Med 49:1082–7. |
| Anderson 2009 J Am Coll Cardiol | 2009 | Anderson EJ, Kypson AP, Rodriguez E, Anderson CA, Lehr EJ, Neufer PD (2009) Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart. J Am Coll Cardiol 54:1891-8. |
| Anderson 2009 J Clin Invest | 2009 | Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin C-T, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD (2009) Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119:573-81. |
O2k-Abstracts
| Published | Reference | |
|---|---|---|
| Neufer 2014 Abstract MiP2014 | 2014 | Assessing ATP production and oxygen consumption simultaneously in permeabilized fibers: ATP/O. |
We continue to "spread the word" about the OROBOROS with our colleagues at meetings and conferences. As with all quality products, I'm not surprised to hear that demand is steady, even in the face of economic hardships. Yours has the added benefit of sophisticated science and precision manufacturing, which exponentially increases its value. Darrell Neufer and I have a big paper being published in JCI on this upcoming Monday (on-line first). There is OROBOROS data all over it. Many more papers are currently being written, as we've been using our O2k's at maximal capacity for the past two years! Would it be possible for you to send a small stack of your "Blue Book of Mitochondria" with the new O2k? It's really an invaluable resource for students and new people that join the lab. - Ethan J Anderson
