WG2 MitoEAGLE data: muscle

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Management Committee

Members

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

WG2 MitoEAGLE data: muscle

WG2 Action

MitoEAGLE data repository on muscle tissues

»WG2 Project application

WG2 Action

WG Leader

Pablo Miguel Garcia-Roves, PhD. - [email protected]

WG Co-Leader

Terje Larsen, Prof., Dr. - [email protected]

Participants and discussion

» Talk:MitoEAGLE data: muscle

Task groups

TG leaders: suggestions discussed at the MitoFit Science Camp 2016 Kuehtai AT.

TG participants: listed as a summary from the feedback received.

TG2.1 Skeletal

TG leaders: Garcia-Roves Pablo M ES / Votion Dominique-Marie BE / Coen Paul M US

TG participants: Boyle John P UK, Chabi Beatrice FR, Garcia-Roves Pablo MES, Lehti Maarit FI, Mars Tomaz SI, Pirkmajer Sergej SI, Rustan Arild NO, Schlattner UweFR, Wuest Rob C NL, Doerrier Velasco CA AT

TG2.2 Cardiac

TG leaders: Larsen Terje S NO / Makrecka-Kuka Marina LV

TG participants: Muntean Danina M RO , Schlattner Uwe FR, Vendelin Marko EE, Wuest Rob C NL, Doerrier Velasco CA AT

Progress

» WG2 summary - Belgrade

» MiPschool Coimbra 2019 - Presentation of review article on diabetic heart which has been submitted to Acta Physiologica and report on WG2 status of the soleus study and the human muscle studies

» WG2 Session - Copehagen 2019

» MitoEAGLE Tromso 2019 - WG 2 Retreat for the review paper “Altered function of cardiac mitochondria in diabetes and obesity”

» MitoEAGLE Obergurgl 2019-01-31

» WG2 summary - Jurmala

WG2: MitoEAGLE data repository in skeletal and cardiac muscle

• Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers
• Inter-laboratory study on human permeabilized myofibres: effects of fibre preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation
• Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report

» MitoEAGLE Copenhagen 2018

» WG2 summary - Hradec Kralove

» WG2 summary - Obergurgl

» Minutes with WG2 summary - Barcelona

» MiPMap

Open call

Working group 2 open call

Next steps

» MitoEAGLE data repository in muscle tissues