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Difference between revisions of "Electron leak"

From Bioblast
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{{MitoPedia
{{MitoPedia
|description=The flux of electrons that exit the electron transfer system without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the Δp. In some cases, the Δp dependance relies more on the ΔpH component than in the ΔΨ.
|description=The flux of electrons that exit the electron transfer system without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the Δp. In some cases, the Δp dependance relies more on the ΔpH component than in the ΔΨ.
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{{MitoPedia concepts
 
|mitopedia concept=MiP concept
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{{MitoPedia methods
|mitopedia method=Respirometry, Fluorometry
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{{MitoPedia O2k and high-resolution respirometry}}
{{MitoPedia topics
|mitopedia topic=EAGLE
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|mitopedia method=Respirometry
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{{MitoPedia topics
|mitopedia topic=EAGLE
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Revision as of 10:13, 5 March 2019


high-resolution terminology - matching measurements at high-resolution


Electron leak

Description

The flux of electrons that exit the electron transfer system without completing the reduction of oxygen to water at cytochrome c, causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the Δp. In some cases, the Δp dependance relies more on the ΔpH component than in the ΔΨ.


MitoPedia concepts: MiP concept 


MitoPedia methods: Respirometry, Fluorometry 



MitoPedia topics: EAGLE 

Questions.jpg


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