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Difference between revisions of "Electron leak"

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|description=Electrons that escape the [[electron transfer system]] without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of [[Reactive_oxygen_species |ROS]]. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the [[Protonmotive force|Δ''p'']]. In some cases, the [[Protonmotive force|Δ''p'']] dependance relies more on the ∆pH component than in the ∆''Ψ''.
|description=Electrons that escape the [[electron transfer system]] without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of [[Reactive_oxygen_species |ROS]]. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the [[Protonmotive force|Δ''p'']]. In some cases, the [[Protonmotive force|Δ''p'']] dependance relies more on the ∆pH component than in the ∆''Ψ''.
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{{MitoPedia concepts
{{MitoPedia concepts
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Revision as of 09:37, 5 March 2019


high-resolution terminology - matching measurements at high-resolution


Electron leak

Description

Electrons that escape the electron transfer system without completing the reduction of oxygen to water at cytochrome c, causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the Δp. In some cases, the Δp dependance relies more on the ∆pH component than in the ∆Ψ.


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MitoPedia concepts: MiP concept 


MitoPedia methods: Respirometry, Fluorometry 



MitoPedia topics: EAGLE