Difference between revisions of "Electron leak"
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|description=Electrons that escape the [[electron transfer system]] without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of [[Reactive_oxygen_species |ROS]]. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the [[Protonmotive force|Δ''p'']]. In some cases, the [[Protonmotive force|Δ''p'']] dependance relies more on the ∆pH component than in the ∆''Ψ''. | |description=Electrons that escape the [[electron transfer system]] without completing the reduction of oxygen to water at cytochrome ''c'', causing the production of [[Reactive_oxygen_species |ROS]]. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the protonmotive force ([[Protonmotive force|Δ''p'']]). In some cases, the [[Protonmotive force|Δ''p'']] dependance relies more on the ∆pH component than in the ∆''Ψ''. | ||
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Revision as of 10:38, 5 March 2019
- high-resolution terminology - matching measurements at high-resolution
Electron leak
Description
Electrons that escape the electron transfer system without completing the reduction of oxygen to water at cytochrome c, causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the protonmotive force (Δp). In some cases, the Δp dependance relies more on the ∆pH component than in the ∆Ψ.
- » Keywords: electron leak
MitoPedia concepts:
MiP concept
MitoPedia methods:
Respirometry,
Fluorometry
MitoPedia topics: EAGLE
