Description
The flux of electrons that exit the electron transfer system without completing the reduction of oxygen to water at cytochrome c, causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the ฮp. In some cases, the ฮp dependance relies more on the ฮpH component than in the ฮฮจ.
MitoPedia methods:
Respirometry