Description
Electrons that escape the electron transfer system without completing the reduction of oxygen to water at cytochrome c, causing the production of ROS. The rate of electron leak depends on the topology of the complex, the redox state of the moiety responsible of electron leakiness and usually on the Δp. In some cases, the Δp dependance relies more on the ∆pH component than in the ∆Ψ.
- » Keywords: electron leak
MitoPedia concepts:
MiP concept
MitoPedia methods:
Respirometry,
Fluorometry
MitoPedia topics: EAGLE