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Linearity

From Bioblast


high-resolution terminology - matching measurements at high-resolution


Linearity

Description

Linearity is the ability of the method to produce test results that are proportional, either directly or by a well-defined mathematical transformation, to the concentration of the analyte in samples within a given range. This property is inherent in the Beer-Lambert law for absorbance alone, but deviations occur in scattering media. It is also a property of fluorescence, but a fluorophore may not exhibit linearity, particularly over a large range of concentrations.


Reference: Paul WL (1991) USP perspectives on analytical methods evaluation. Pharm. Technol. 15: 130-141. Elwell CE (1995) A practical users guide to near infrared spectroscopy. Hamamatsu Photonics, 155pp.


MitoPedia concepts: "MitoFit Quality Control System" is not in the list (MiP concept, Respiratory state, Respiratory control ratio, SUIT concept, SUIT protocol, SUIT A, SUIT B, SUIT C, SUIT state, Recommended, ...) of allowed values for the "MitoPedia concept" property. MitoFit Quality Control System"MitoFit Quality Control System" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 


MitoPedia methods: Respirometry, Fluorometry, Spectrophotometry 




Contributed by Harrison DK, 2011-11-18