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Difference between revisions of "MitoKit-CII MitoPedia"

From Bioblast
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::::* NV118/MitoKit-CII: 100 mM stock solution - more details [[NV118/MitoKit-CII|here]]
::::* NV118/MitoKit-CII: 100 mM stock solution - more details [[NV118/MitoKit-CII|here]]
::::* NV161/MitoKit-CII: 10 mM stock solution - more details [[NV161/MitoKit-CII|here]]
::::* NV161/MitoKit-CII: 10 mM stock solution - more details [[NV161/MitoKit-CII|here]]
== SUITbrowser question: Permeable succinate/malonate ==
Work in progress

Revision as of 14:30, 13 May 2019


high-resolution terminology - matching measurements at high-resolution


MitoKit-CII MitoPedia

Description

Cell permeable prodrugs, composed of NV161/MitoKit-CII and NV118/MitoKit-CII, of the Complex II substrate succinate increase ATP-linked mitochondrial respiration in CI-deficient human blood cells, fibroblasts and heart fibres.

Abbreviation: MitoKit-CII

Reference: MitoKit-CII, Ehinger 2016 Nat Commun


MitoPedia topics: Media for respirometry 



Application in HRR

Preparation

Both compounds are dissolved in DMSO and stored in aliquots at -20 Β°C.
We recommend the following dilutions for reaching the desired concentration in the experiments:


  • NV118/MitoKit-CII: 100 mM stock solution - more details here
  • NV161/MitoKit-CII: 10 mM stock solution - more details here


SUITbrowser question: Permeable succinate/malonate

Work in progress