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Difference between revisions of "Oxidative phosphorylation"

From Bioblast
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|description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of [[ADP]] to [[ATP]] and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (''P'') of respiration provides a measure of [[OXPHOS capacity]], which is frequently corrected for [[residual oxygen consumption]] (ROX).
|description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of [[ADP]] to [[ATP]] and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (''P'') of respiration provides a measure of [[OXPHOS capacity]], which is frequently corrected for [[residual oxygen consumption]] (ROX).
|info=[[OXPHOS capacity]]
|info=[[OXPHOS capacity]]
|type=Respiration
}}
{{MitoPedia concepts
|mitopedia concept=Respiratory state
|type=Respiration
|type=Respiration
}}
}}
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|type=Respiration
|type=Respiration
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{{MitoPedia topics
{{MitoPedia O2k and high-resolution respirometry|type=Respiration
|mitopedia topic=Respiratory state
}}
|type=Respiration
{{MitoPedia topics|type=Respiration
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}}
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase ([[Gnaiger 2014 MitoPathways]]).]]
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase ([[Gnaiger 2014 MitoPathways]]).]]

Revision as of 14:02, 8 February 2016


high-resolution terminology - matching measurements at high-resolution


Oxidative phosphorylation

Description

P.jpg Oxidative phosphorylation (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of ADP to ATP and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (P) of respiration provides a measure of OXPHOS capacity, which is frequently corrected for residual oxygen consumption (ROX).

Abbreviation: OXPHOS

Reference: OXPHOS capacity


MitoPedia concepts: Respiratory state 


MitoPedia methods: Respirometry 




Energy transformation in coupled fluxes, J, and forces, F and Ξ”p, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (Gnaiger 2014 MitoPathways).

OXPHOS

Figure: Energy transformation in coupled fluxes, J, and forces, F and Ξ”p, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (from Gnaiger 2014).


Related terms in Bioblast

P.jpg OXPHOS, P

R.jpg ROUTINE, R

E.jpg ETS, E

L.jpg LEAK, L

ROX.jpg ROX