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Difference between revisions of "Oxidative phosphorylation"

From Bioblast
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{{MitoPedia
{{MitoPedia
|abbr=OXPHOS
|abbr=OXPHOS
|description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced substrates with electron transfer to oxygen, coupled to the phosphorylation of [[ADP]] to [[ATP]] and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (''P'') of respiration provides a measure of [[OXPHOS capacity]], which is frequently corrected for [[residual oxygen consumption]] (ROX).
|description=[[File:P.jpg |link=OXPHOS capacity]] '''Oxidative phosphorylation''' (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of [[ADP]] to [[ATP]] and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (''P'') of respiration provides a measure of [[OXPHOS capacity]], which is frequently corrected for [[residual oxygen consumption]] (ROX).
|info=[[Gnaiger 2014 MitoPathways]]
|info=[[Gnaiger 2014 MitoPathways]]
|type=Respiration
|type=Respiration
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|type=Respiration
|type=Respiration
}}
}}
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of trans-located protons from low pH in the positive P-phase to the negative N-phase ([[Gnaiger 2012 MitoPathways]]).]]
[[Image:OXPHOS-coupled energy cycles.jpg|400px|link=Gnaiger 2012 MitoPathways|thumb|Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H<sup>+</sup>out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase ([[Gnaiger 2014 MitoPathways]]).]]


== OXPHOS ==
== OXPHOS ==


'''Figure''': Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO substrates and electron transfer to oxygen. ''J''<sub>H+out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (from [[Gnaiger 2012 MitoPathways |Gnaiger 2012]]).
'''Figure''': Energy transformation in coupled fluxes, ''J'', and forces, ''F'' and Ξ”''p'', of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. ''J''<sub>H+out</sub> is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (from [[Gnaiger 2014 MitoPathways |Gnaiger 2014]]).




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== Related terms in Bioblast ==
== Related terms in Bioblast ==
[[File:P.jpg |link=OXPHOS capacity]] [[OXPHOS capacity |OXPHOS]], ''P''
[[File:P.jpg |link=OXPHOS capacity]] [[OXPHOS capacity |OXPHOS]], ''P''
[[File:R.jpg |link=ROUTINE respiration]] [[ROUTINE respiration |ROUTINE]], ''R''


[[File:E.jpg |link=ETS capacity]] [[ETS capacity |ETS]], ''E''
[[File:E.jpg |link=ETS capacity]] [[ETS capacity |ETS]], ''E''
[[File:R.jpg |link=ROUTINE respiration]] [[ROUTINE respiration |ROUTINE]], ''R''


[[File:L.jpg |link=LEAK respiration]] [[LEAK respiration |LEAK]], ''L''
[[File:L.jpg |link=LEAK respiration]] [[LEAK respiration |LEAK]], ''L''


[[File:ROX.jpg]] [[Residual oxygen consumption |ROX]]
[[File:ROX.jpg]] [[Residual oxygen consumption |ROX]]

Revision as of 10:59, 2 November 2014


high-resolution terminology - matching measurements at high-resolution


Oxidative phosphorylation

Description

P.jpg Oxidative phosphorylation (OXPHOS) is the oxidation of reduced fuel substrates by electron transfer to oxygen, chemiosmotically coupled to the phosphorylation of ADP to ATP and accompanied by an intrinsically uncoupled component of respiration. The OXPHOS state (P) of respiration provides a measure of OXPHOS capacity, which is frequently corrected for residual oxygen consumption (ROX).

Abbreviation: OXPHOS

Reference: Gnaiger 2014 MitoPathways


MitoPedia methods: Respirometry 


MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 

Energy transformation in coupled fluxes, J, and forces, F and Ξ”p, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (Gnaiger 2014 MitoPathways).

OXPHOS

Figure: Energy transformation in coupled fluxes, J, and forces, F and Ξ”p, of oxidative phosphorylation. 2[H] indicates the reduced hydrogen equivalents of CHO fuel substrates and electron transfer to oxygen. JH+out is coupled output flux. Proton leaks dissipate energy of translocated protons from low pH in the positive P-phase to the negative N-phase (from Gnaiger 2014).


Related terms in Bioblast

P.jpg OXPHOS, P

R.jpg ROUTINE, R

E.jpg ETS, E

L.jpg LEAK, L

ROX.jpg ROX