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This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.

List of results

• '''''J''_max''' is t … '''''J''_max''' is the maximum pathway flux (e.g. [[oxygen flux]]) obtained at saturating substrate concentration. ''J''_max is a function of metabolic state. In hyperbolic ADP or oxygen kinetics, ''J''_max is calculated by extrapolation of the hyperbolic function, with good agreement between the calculated and directly measured fluxes, when substrate levels are >20 times the ''c''₅₀ or [[P50|''p''₅₀]].[[P50|''p''₅₀]].  +
• '''''N,N,N',N'''-Tetramethyl-''p''-phenyle … '''''N,N,N',N'''-Tetramethyl-''p''-phenylenediamine dihydrochloride, TMPD''', is applied as an artificial substrate for reducing [[cytochrome c|cytochrome ''c'']] in the respirometric assay for [[Complex IV|cytochrome ''c'' oxidase]] (CIV) activity. It is maintained in a reduced state by [[ascorbate]] and undergoes [[autoxidation]] as a function of [[oxygen pressure]], TMPD, ascorbate and cytochrome ''c'' concentration.orbate and cytochrome ''c'' concentration.  +
• '''''p''₅₀''' is th … '''''p''₅₀''' is the oxygen partial pressure at which (a) respiratory flux is 50% of maximum oxygen flux, [[Jmax|''J''_max]], at saturating oxygen levels. The oxygen affinity is indirectly proportional to the ''p''₅₀. The ''p''₅₀ depends on metabolic state and rate. (b) ''p''₅₀ is the oxygen partial pressure at which oxygen binding (on myoglobin, haemoglobin) is 50%, or desaturation is 50%.n partial pressure at which oxygen binding (on myoglobin, haemoglobin) is 50%, or desaturation is 50%.  +
• '''2,4-dinitrophenole''' (C₆H₄N₂O₅; M = 184.11 g·mol^-1) is a protonophore acting as an [[uncoupler]] of [[oxidative phosphorylation]].  +
• '''2-Deoxyglucose''', also known as 2-deoxy-D-glucose is a glucose derivative that has the 2-hydroxyl group replaced by hydrogen. It competitively inhibits glycolysis by blocking hexokinase and phosphohexoseisomerase.  +
• '''2-mercaptoacetate''' is an inhibitor of … '''2-mercaptoacetate''' is an inhibitor of medium-chain acyl-CoA dehydrogenase, MCAD, the rate-limiting enzyme of [[octanoylcarnitine]] oxidation. 2-mercaptoacetate has been used as an inhibitor of [[fatty acid oxidation]] ([[F-pathway control state]]). In permeabilized rat soleus muscle fibers, pre-incubation with 1 mM 2-mercaptoacetate for 45 min resulted in 58% inhibition of MCAD and decreased [[octanoylcarnitine]]&[[malate]] stimulated respiration by approximately 60% ([[Osiki 2016 FASEB J]]).[[Osiki 2016 FASEB J]]).  +
• '''4'''#### '''''O2k-Catalogue: O2k-Modules'''''. O2k-Modules can be obtained with the O2k or added later, and can be simply installed by the user.  +
• '''4,5,6,7-Tetrachloro-2-trifluoromethylbenzimidazole''' is a protonophore or [[uncoupler]] of oxidative phosphorylation.  +
• '''8-Hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS)''' is a ratiometric pH fluorophore; pKa = 7.3. Relative molecular mass: ''M''_r = 524.39  +
• '''AMP-activated protein kinase''' is a regulatory protein which acts as crucial cellular energy sensor by sensing AMP, [[ADP]] and/or Ca²⁺ levels in response to metabolic stresses or drug administration.  +
• '''ATP synthase''' or F-ATPase (F<sub&g … '''ATP synthase''' or F-ATPase (F₁F_O-ATPase; the use of Complex V is discouraged) catalyzes the [[endergonic]] phosphorylation of [[ADP]] to [[ATP]] in an over-all [[exergonic]] process that is driven by proton translocation along the [[protonmotive force]]. The ATP synthase can be inhibited by [[oligomycin]].[[oligomycin]].  +
• '''ATPases''' are enzymes that hydrolyse [[ATP]] … '''ATPases''' are enzymes that hydrolyse [[ATP]], releasing [[ADP]] and [[inorganic phosphate]]. The contamination of isolated mitochondria with ATPases from other organelles and endogenous adenylates can lead to the production of ADP, which can stimulate respiration. This situation would lead to an overestimation of [[LEAK respiration]] measured in the absence of ADP, ''L''(n) and subsequent inhibition of respiration by oligomycin, ''L''(Omy). of respiration by oligomycin, ''L''(Omy).  +
• '''Acceleration''', '''''a''''', is the ch … '''Acceleration''', '''''a''''', is the change of [[velocity]] over time [m·s^-2].</br> '''''a''''' = d'''''v'''''/d''t''</br>The symbol ''g'' is used for acceleration of free fall. The standard acceleration of free fall is defined as ''g''_n = 9.80665 [m·s^-2].ned as ''g''_n = 9.80665 [m·s^-2].  +
• '''Acclimation''' is an immediate time scale adaption expressing phenotypic plasticity in response to changes of a single variable under controlled laboratory conditions.  +
• '''Acclimatization''' is an immediate time scale adaption expressing phenotypic plasticity in response to changes of habitat conditions and life style where several variables may change simultaneously.  +
• '''Acyl-CoA dehydrogenases''' ACADs are lo … '''Acyl-CoA dehydrogenases''' ACADs are localized in the mitochondrial matrix. Several ACADs are distinguished: short-chain (SCAD), medium-chain (MCAD), and long-chain (LCAD). ACAD9 is expressed in human brain. ACADs catalyze the reaction</br>:::: acyl-CoA + FAD → ''trans''-2-enoyl-CoA + FADH₂→ ''trans''-2-enoyl-CoA + FADH₂  +
• '''Acyl-CoA oxidase''' is considered as a … '''Acyl-CoA oxidase''' is considered as a rate-limiting step in peroxysomal ''β''-oxidation, which carries out few ''β''-oxidation cycles, thus shortening very-long-chain fatty acids (>C₂₀). Electrons are directly transferred from FADH₂ to O₂ with the formation of H₂O₂.t; to O₂ with the formation of H₂O₂.  +
• '''Acylcarnitines''' are esters derivative … '''Acylcarnitines''' are esters derivative of [[carnitine]] and [[fatty acid]]s, involved in the metabolism of fatty acids. Long-chain acylcarnitines such as [[palmitoylcarnitine]] must be transported in this form, conjugated to carnitine, into the mitochondria to deliver fatty acids for fatty acid oxidation and energy production. Medium-chain acylcarnitines such as [[octanoylcarnitine]] are also frequently used for high-resolution respirometry.tly used for high-resolution respirometry.  +
• '''Adaptation''' is an evolutionary time scale expression of phenotypic plasticity in response to selective pressures prevailing under various habitat conditions.  +
• '''Add:''' A new graph is added at the bottom of the screen. Select plots for display in the new graph, Ctrl+F6. '''Delete: Delete one of the graphs displayed in DatLab.  +