Template:Next oroboros ecosystem agenda

2021 Week 48

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Targeting mitochondrial translation – a potential therapeutic strategy to suppress glioblastoma stem cell growth

Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, Soldano A, Adami V, Ambrosini C, Broso F, Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG, Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J, Pallini R, Roulland S, Amunts A, Mancini I, Modelska A, Quattrone A (2021) Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep 35:109024. »Bioblast link«

from the O2k-Network »IT Bolzano Pichler I«

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2021 Week 49

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What is ROUTINE respiration?

ROUTINE respiration is the respiratory activity of living (non-permeabilized) cells in the physiological coupling state, which is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation.
- »Gnaiger 2020 BEC MitoPathways - Chapter 2.4«
- communicated by »Komlodi Timea« and »Schmitt Sabine«

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How do you measure ROUTINE respiration?

ROUTINE respiration (R) of living cells is measured before permeabilization of the cell membrane either in cell culture medium or any other respiration media (e.g. MiR05) in the presence or absence of exogenous substrates. Allow R to stabilize for 15-20 min.
- »ROUTINE respiration« and »Doerrier 2018 Methods Mol Biol«
- communicated by »Komlodi Timea« and »Schmitt Sabine«

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2021 Week 50

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»10th Conference of the International Coenzyme Q10 Association 2022 Hamburg DE« May 12-15

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