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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Lopez MG
MitoPedia topics: EAGLE
COST: Member
COST WG4: WG4
Name | Lopez Manuela G., MD, PhD |
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Institution | Departamento de Farmacolog铆a
Facultad de Medicina |
Address | C/Arzobispo Morcillo 4, 28029 |
City | Madrid |
State/Province | |
Country | Spain |
[email protected] | |
Weblink | |
O2k-Network Lab |
Labels:
Publications
Published | Reference | |
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Hernansanz-Agustin 2020 Nature | 2020 | Hernansanz-Agust铆n P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Pi帽a T, Moreno L, Izquierdo-脕lvarez A, Cabrera-Garc铆a JD, Cort茅s A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antol铆n A, Tello D, Ac铆n-P茅rez R, Rodr铆guez-Aguilera JC, Navas P, Cogolludo 脕, L贸pez-Montero I, Mart铆nez-Del-Pozo 脕, Egea J, L贸pez MG, Elrod JW, Ru铆z-Cabello J, Bogdanova A, Enr铆quez JA, Mart铆nez-Ruiz A (2020) Na+ controls hypoxic signalling by the mitochondrial respiratory chain. Nature 586:287-91. |
Hernansanz-Agustin 2019 bioRxiv | 2019 | Hernansanz-Agust铆n P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Pi帽a T, Moreno L, Izquierdo-脕lvarez A, JCabrera-Garc铆a JD, Cort茅s A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antol铆n A, Tello D, Ac铆n-P茅rez R, Rodr铆guez-Aguilera JC, Navas P, Cogolludo A, L贸pez-Montero I, Mart铆nez-del-Pozo A, Egea J, L贸pez MG, Elrod JW, Ruiz-Cabello J, Bogdanova A, Enr铆quez JA, Mart铆nez-Ruiz A (2019) Mitochondrial Na+ import controls oxidative phosphorylation and hypoxic redox signalling. bioRxiv doi: https://doi.org/10.1101/385690. |
Moreno-Ortega 2015 Aging Cell | 2015 | Moreno-Ortega AJ, Buendia I, Mouhid L, Egea J, Lucea S, Ruiz-Nu帽o A, L贸pez MG, Cano-Abad MF (2015) CALHM1 and its polymorphism P86L differentially control Ca2+ homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid 尾. Aging Cell 14:1094-102. |
Guerra-Alvarez 2015 J Neurochem | 2015 | Guerra-脕lvarez M, Moreno-Ortega AJ, Navarro E, Fern谩ndez-Morales JC, Egea J, L贸pez MG, Cano-Abad MF (2015) Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca2+ release from the endoplasmic reticulum. J Neurochem 133:309-19. |
Abstracts
MitoEAGLE Feedback
- My interest in joining this COST action is because I am recently working in mitochondrial biogenesis and also with some compounds that interfere with mitochondrial function. My main research interest has do with neuroprotection in neurodegenerative diseases and brain ischemia conditions where mitochondrial dysfunction has a pivotal role in their pathogenesis; we thereby try to find therapeutic strategies bases on restoring mitochondrial function. I believe the interaction with other members of this COST action can bring about interesting collaborations to support: (i) our knowledge on mitochondrial function and develop new drugs for identities that still do not have efficient treatments and (ii) improve our knowledge on the involvement of mitochondrial dysfunction in these diseases. - Manuela Lopez (2016).