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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Vinogradov Andrei D
MitoPedia topics: EAGLE
Name | Vinogradov Andrey D., Prof. Dr. ORCID ID (1942-2021) |
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Institution | Dept. of Biochemistry
Moscow State University |
Address | , |
City | Moscow |
State/Province | |
Country | Russia |
Weblink | Research.com |
O2k-Network Lab |
A tribute to Andrei Vinogradov
- Communicated by Alexander Galkin - Tributes to pioneers in bioenergetics
- Professor Andrei Vinogradov was a distinguished Russian biochemist, whose contributions have left a lasting mark on the field of bioenergetics. Renowned for his groundbreaking research in mitochondrial biochemistry, Andrei Vinogradov's career spanned decades of dedicated inquiry and discovery.
- Andrei started his scientific career at Moscow State University in the former USSR in 1964. He obtained his postdoctoral training with several world-renowned bioenergetisists: Britton Chance, Efraim Racker, and Thomas Singer. There, he focused on the purification and characterization of mitochondrial membrane proteins, laying the groundwork for his future achievements.
- In the 70βs, he established a laboratory in the Biochemistry Department of Moscow University where he flourished. Over the years, his team conducted systematic analyses of enzymatic properties of key mitochondrial enzymes such as succinate dehydrogenase, calcium transporter, ATP-synthase, and Complex I. In the 60βs, Andrei was among the pioneering scientists investigating reverse electron transfer β recently emerged as a key driver of several metabolic pathways. His group predicted the structure of the active center of mitochondrial succinate dehydrogenase, later confirmed by X-ray analysis. In the early 90βs he described and biochemically characterized the active/deactive conformational transition of mitochondrial Complex I, which became a dynamic area of research in the studies of tissue ischemia/reperfusion injury.
- He was an excellent violinist and a dazzling lecturer and presenter. His General Biochemistry and Enzyme Kinetics lectures were the most memorable events for many of his students in the last three decades and served as a beacon of inspiration for future generations of scientists.
- This tribute, prepared by Andrei's colleagues and disciples honors his remarkable contributions to bioenergetics and his influence on the scientific community.
Tributes to pioneers in bioenergetics - wandering in the garden of memories
Mitochondria and bioblasts: Made history
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Publications
Published | Reference | |
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BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al β MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 |
Grivennikova 2018 Redox Biol | 2018 | Grivennikova VG, Kareyeva AV, Vinogradov AD (2018) Oxygen-dependence of mitochondrial ROS production as detected by Amplex Red assay. Redox Biol 17:192-9. |
Vinogradov 2005 Biochemistry (Mosc) | 2005 | Vinogradov AD, Grivennikova VG (2005) Generation of superoxide-radical by the NADH:ubiquinone oxidoreductase of heart mitochondria. Biochemistry (Mosc) 70:120-7. |