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| {{Template:OROBOROS banner}}
| | #REDIRECT [[OROBOROS_INSTRUMENTS]] |
| {{Template:OROBOROS navigation line}}
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| [[Image:Logo OROBOROS INSTRUMENTS.jpg|right|380px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS|OROBOROS INSTRUMENTS]]
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| :::::: <big><big><big>'''Mitochondria and cell research'''</big></big></big>
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| <br />
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| [[Image:O2k-Fluorometer.JPG|120px|left|link=http://wiki.oroboros.at/index.php/O2k-Fluorometer|O2k-Fluorometer]]
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| ::::: <big><big><big>'''Oxygraph-2k and''' </big></big></big>
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| ::::: <big><big><big>'''O2k-Fluorometer'''</big></big></big>
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| <br />
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| :::::: '''<big>High-resolution respirometry (HRR)</big>'''
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| ::::::: <big>'''[[O2k-Network]]'''</big>
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| :::::::: <big> [http://www.mitoglobal.org/index.php/MITOEAGLE Mitochondrial fitness mapping: MITOEAGLE].</big>
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| <br />
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| ----
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| == OROBOROS:About ==
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| [[Image:Logo_OROBOROS_INSTRUMENTS.jpg|left|150px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS |OROBOROS]]
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| :::: [[OROBOROS INSTRUMENTS]] distributes the world-wide leading O2k-technology of high-resolution respirometry - '''O2k and HRR'''. The [http://wiki.oroboros.at/index.php/OROBOROS_Contact '''OROBOROS Company'''] is fully scientifically oriented, with emphasis on continuous innovation. The extension of the [[Oxygraph-2k]] (O2k) to the [[O2k-Fluorometer]] has set a new standard for O2k-MultiSensor approaches (see [[OROBOROS O2k-Catalogue]]). The O2k is established internationally, with {{#ask:[[Category:Publications]][[Instrument and method::Oxygraph-2k]] |format=count}} [[O2k-Publications: Topics|O2k-Publications]] in the scientific literature. OROBOROS has organized more than 100 international [[OROBOROS_Events#Next_O2k-Workshops |O2k-Workshops]]. The [[O2k-Network]] includes {{#ask:[[Category:O2k-Network]] |format=count}} Reference Laboratories in 49 countries.
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| == [[O2k |The O2k for high-resolution respirometry]] ==
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| [[Image:O2k-Fluorometer.JPG|left|150px|link=http://wiki.oroboros.at/index.php/Oxygraph-2k |O2k]]
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| :::: O2k is the acronym for the OROBOROS '''[[Oxygraph-2k]]''' and '''[[O2k-Fluorometer]]''' - the modular system for high-resolution respirometry and mitochondrial physiology. The O2k provides a unique high-resolution approach for the monitoring of cellular and mitochondrial respiratory function: [[high-resolution respirometry |high-resolution respirometry (HRR)]]. Considering mitochondria as the powerhouses of the cell, HRR introduced the concept of [[cell ergometry]]. Are your cells [[MitoFit]]?
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| :::: HRR is applied [[O2k-Network |world-wide]] in areas ranging from fundamental bioenergetics to the analysis of mitochondrial and metabolic diseases, advancing the rapidly growing field of preventive mitochondrial medicine. Mitochondrial fitness needs to be monitored in a variety of age-related health risks, including cardiovascular and degenerative diseases, such as type 2 diabetes, neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s), and several types of cancer.
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| == [[OROBOROS MitoFit Laboratory]] ==
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| [[File:OROBOROS MitoFit-Lab.jpg|left|240px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS |OROBOROS]]
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| :::: HRR by the OROBOROS O2k is based on a radically different systems approach to polarographic measurement of oxygen dynamics. HRR rests on several tightly connected instrumental features and concepts integrated by the DatLab software, providing real-time display of oxygen concentration and respiration ([[oxygen flux]]). The mechanics, critical selection of materials, and state-of-the-art electronics provide the basis of signal stability of an optimized [[polarographic oxygen sensor]], in an electronically controlled thermal environment with high temperature stability. Calibrations and instrumental controls follow standard operating procedures, with highly automatic real-time analysis by the DatLab software. Scientific support is complementary to the approach of HRR.
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| == [[Cell ergometry]] ==
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| [[File:EPL-free and excess.jpg|left|240px|link=Gnaiger 2014 MitoPathways |Gnaiger 2014 MitoPathways]]
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| ::::* '''»''' A concept complete with elaborated protocols, to get started and gain competence in the expanding field of bioenergetics: » [[Gnaiger 2014 MitoPathways |Blue Book 2014]] - » [[O2k-Protocols]].
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| ::::* '''»''' Explore cell respiration and key mitochondrial functions''': [[High-resolution respirometry |» HRR]] and the [http://www.oroboros.at/?Oxygraph » O2k].
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| ::::* '''»''' Introductory courses and advanced training: » [[OROBOROS_Events]].
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| ::::'''»''' [http://www.oroboros.at/?Purchase WorldWide distribution].
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| == OROBOROS navigation ==
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| ::::'''»''' [[OROBOROS navigation]]
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