Bristot 2014 Abstract MiP2014
| High-resolution respirometry and bioenergetics evaluation in fibrobalsts derived from patient with TP53 germline mutations. |
Link:
MiP2014, Book of Abstracts Open Access
Bristot IJ, Macedo G, Neto CB, Ashton-Prolla P, Klamt F (2014)
Event: MiP2014
Labels: MiParea: Respiration Pathology: Cancer Stress:RONS; Oxidative Stress"RONS; Oxidative Stress" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Human
Preparation: Intact cells
Coupling state: LEAK, OXPHOS
HRR: Oxygraph-2k
MiP2014
Affiliation
1-Progr Pós-Gradua Ciências Biol: Bioquímica, UFRGS; 2-Inst Nacionais Ciência e Tecnol - Translac Medicina; 3-Progr Pós-Gradua Genét Biol Mol, Univ Federal Rio Grande do Sul (UFRGS); 4-Lab Medicina Genômica, Hosp Clínicas Porto Alegre HCPA; 5-Rede Gaúcha Estresse Oxidativo e Sinalização Celular; 6-Progr de Pós-Gradua Ciências Médicas: Medicina, UFRGS, 7Serviço de Genética Médica, HCPA; Porto Alegre, Brazil. - [email protected]
References
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- Latronico AC, Pinto EM, Domenice S, Fragoso MC, Martin RM, Zerbini MC, Lucon AM, Mendonca BB (2001) An inherited mutation outside the highly conserved DNA-binding domain of the p53 tumor suppressor protein in children and adults with sporadic adrenocortical tumors. J Clin Endocrinol Metab 86: 4970–3.
- Cantor JR, Sabatini DM ( 2012) Cancer cell metabolism: one hallmark, many faces. Cancer Discov 2: 881–98.
- Macedo GS, Lisbôa da Motta L, Giacomazzi J, Netto CB, Manfredini V, Vanzin CS, Vargas CR, Hainaut P, Klamt F, Ashton-Prolla P (2012) Increased oxidative damage in carriers of the germline. TP53 p.R337H mutation. PLoS One 7:e47010.
