Dyscoupled respiration: Difference between revisions
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In addition to intrinsic [[uncoupling]], dyscoupling occurs under pathological and toxicological conditions. Thus a distinction is made between physiological uncoupling and pathologically defective dyscoupling in mitochondrial respiration. | In addition to intrinsic [[uncoupling]], dyscoupling occurs under pathological and toxicological conditions. Thus a distinction is made between physiological uncoupling and pathologically defective dyscoupling in mitochondrial respiration. | ||
|info=[[Pesta_2010_Protocols]] | |info=[[Pesta_2010_Protocols]] | ||
|type=Respiration | |||
}} | |||
{{MitoPedia methods | |||
|mitopedia method=Respirometry | |||
|type=Respiration | |type=Respiration | ||
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Revision as of 19:49, 15 November 2011
- high-resolution terminology - matching measurements at high-resolution
Dyscoupled respiration
Description
[[Description::Dyscoupled respiration is distinguished from intrinsically (physiologically) uncoupled and from extrinsic experimentally uncoupled respiration as an indication of extrinsic uncoupling (pathological, toxicological, pharmacological by agents that are not specifically applied to induce uncoupling, but are tested for their potential dyscoupling effect). Dyscoupling indicates a mitochondrial dysfunction.
In addition to intrinsic uncoupling, dyscoupling occurs under pathological and toxicological conditions. Thus a distinction is made between physiological uncoupling and pathologically defective dyscoupling in mitochondrial respiration.]]
Reference: [[Info::Pesta_2010_Protocols]]
MitoPedia methods:
Respirometry
MitoPedia topics:
MitoPedia topic::Respiratory state
