Glycerophosphate: Difference between revisions

Revision as of 16:25, 20 January 2014

high-resolution terminology - matching measurements at high-resolution

Glycerophosphate

Description

Glycerophosphate (synonym: α-glycerophosphate; glycerol-3-phosphate; C₃H₉O₆P) is an organophosphate and it is a component of glycerophospholipids.

Abbreviation: Gp

MitoPedia topics: Substrate and metabolite

Glycerophosphate feeds electrons directly to ubiquinone and glycerophosphate dehydrogenase oxidizes glycerophosphate to dihydroxyacetone phosphate. See also glycerol phosphate shuttle.

Comment: Sigma does not sell DL-alpha-glycerophosphate disodium salt hexahydrate (FW = 324.1; Sigma G-2138) any more (personal communication with Dr. Zdenek Drahota, Dept. of Bioenergetics, Institute of Physiology, Academy of Sciences of the Czech Rep.)! [In Dr. Drahota's lab a 1 M stock solution is used and the final concentration in the O2k-chamber is 10 mM.]

Search for an adequate replacement is underway.

@@ Line 15: / Line 15: @@
 '''Comment:'''
 ''Sigma does not sell DL-alpha-glycerophosphate disodium salt hexahydrate (FW = 324.1; Sigma G-2138) any more (personal communication with [[Drahota Z|Dr. Zdenek Drahota]], Dept. of Bioenergetics, Institute of Physiology, Academy of Sciences of the Czech Rep.)!''
-: → they prepare a 1 M stock solution and the final concentration in 2 ml O2k-chamber is 10 mM.
+[In Dr. Drahota's lab a 1 M stock solution is used and the final concentration in  the O2k-chamber is 10 mM.]
-'''Now available:''' rac-Glycerol 1-phosphate disodium salt hydrate (synonym: '''DL-α-Glycerophosphate disodium salt hydrate'''), Sigma G-2138, FW = 216.04 (anhydrous basis)
+Search for an adequate replacement is underway.