Difference between revisions of "Jesina 2004 Physiol Res"
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|preparations=Isolated Mitochondria | |preparations=Isolated Mitochondria | ||
|discipline=Mitochondrial Physiology, Biomedicine | |discipline=Mitochondrial Physiology, Biomedicine | ||
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Revision as of 17:18, 25 February 2013
| Jesina P, Kholova D, Bolehovska R, Cervinkova Z, Drahota Z, Houstek J (2004) Glycerophosphate-dependent hydrogen peroxide production by rat liver mitochondria. Physiol Res 53: 305-310. |
Jesina P, Kholova D, Bolehovska R, Cervinkova Z, Drahota Z, Houstek J (2004) Physiol. Res.
Abstract: We studied the extent to which hormonally-induced mitochondrial glycerophosphate dehydrogenase (mGPDH) activity contributes to the supply of reducing equivalents to the mitochondrial respiratory chain in the rat liver. The activity of glycerophosphate oxidase was compared with those of NADH oxidase and/or succinate oxidase. It was found that triiodothyronine-activated mGPDH represents almost the same capacity for the saturation of the respiratory chain as Complex II. Furthermore, the increase of mGPDH activity induced by triiodothyronine correlated with an increase of capacity for glycerophosphate-dependent hydrogen peroxide production. As a result of hormonal treatment, a 3-fold increase in glycerophosphate-dependent hydrogen peroxide production by liver mitochondria was detected by polarographic and luminometric measurements. • Keywords: Rat liver mitochondria, Mitochondrial glycerophosphate dehydrogenase, Triiodothyronine, Hydrogen peroxide
• O2k-Network Lab: CZ_Hradec Kralove_Cervinkova Z
Labels:
Stress:RONS; Oxidative Stress"RONS; Oxidative Stress" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Rat Tissue;cell: Liver Preparation: Isolated Mitochondria"Isolated Mitochondria" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property.
HRR: Oxygraph-2k
