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Difference between revisions of "Jmax"

From Bioblast
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|description='''''J''<sub>max</sub>''' is the maximum pathway flux (e.g. [[oxygen flux]]) obtained at saturating substrate concentration. ''J''<sub>max</sub> is a function of metabolic state. In hyperbolic ADP or oxygen kinetics, ''J''<sub>max</sub> is calculated by extrapolation of the hyperbolic function, with good agreement between the calculated and directly measured fluxes, when substrate levels are >20 times the ''c''<sub>50</sub> or [[P50|''p''<sub>50</sub>]].
|description='''''J''<sub>max</sub>''' is the maximum pathway flux (e.g. [[oxygen flux]]) obtained at saturating substrate concentration. ''J''<sub>max</sub> is a function of metabolic state. In hyperbolic ADP or oxygen kinetics, ''J''<sub>max</sub> is calculated by extrapolation of the hyperbolic function, with good agreement between the calculated and directly measured fluxes, when substrate levels are >20 times the ''c''<sub>50</sub> or [[P50|''p''<sub>50</sub>]].
|info=[[Gnaiger 1998 J Exp Biol]]
|info=[[Gnaiger 1998 J Exp Biol]]
}}
{{MitoPedia concepts
|mitopedia concept=Respiratory state
}}
}}
{{MitoPedia methods
{{MitoPedia methods
|mitopedia method=Respirometry
|mitopedia method=Respirometry
}}
}}
{{MitoPedia O2k and high-resolution respirometry}}
{{MitoPedia topics
{{MitoPedia topics
|mitopedia topic=Respiratory state, Substrate and metabolite
|mitopedia topic=Substrate and metabolite
}}
}}

Revision as of 13:29, 8 February 2016


high-resolution terminology - matching measurements at high-resolution


Jmax

Description

Jmax is the maximum pathway flux (e.g. oxygen flux) obtained at saturating substrate concentration. Jmax is a function of metabolic state. In hyperbolic ADP or oxygen kinetics, Jmax is calculated by extrapolation of the hyperbolic function, with good agreement between the calculated and directly measured fluxes, when substrate levels are >20 times the c50 or p50.

Abbreviation: Jmax

Reference: Gnaiger 1998 J Exp Biol


MitoPedia concepts: Respiratory state 


MitoPedia methods: Respirometry 



MitoPedia topics: Substrate and metabolite