Lalic Nebojsa M

Name	Lalic Nebojsa, Prof.
Institution	University of Belgrade, School of Medicine Institute for Endocrinology
Address	,
City	Belgrade
State/Province
Country	Republic of Serbia
Email	[email protected]
Weblink
O2k-Network Lab	RS Belgrade Lalic NM

MITOEAGLE Feedback

I would propose my participation in the WG1: Standard operating procedures and user requirement document: Protocols, terminology, documentation, considering that the goal of WG1 is to establish an integrated and analytic environment linking mitochondrial respiration with external data (cell physiology, anthropometry, spiroergometry, lifestyle, genomics) in the context of physical fitness evaluation and clinical diagnostics. I could give my active contribution in the phase of making platform that will aggregate the Action’s complete knowledge and provides the ability to make diagnostic profiling associated with diseases in particular tasks:

• Develop reccomendations for quality control, data reporting and data sharing beyond the published record. Develop concepts on Open Access and institutionalised service for data management, data mining and health-care conforming standards of data interpretation
• Provide a summary on strategic dissemination and an education programme for MITOEAGLE.
• Considering that we are in process of buying the oxygraph, thus broading capacities of my lab, I would be happy to open the door of my new lab for the innovative inter-laboratory ring test experiments and together with my team contribute in that phase of the MITOEAGLE Action. I look forward to the establishment of MitoGlobal EAGLE network where, as stated in the MoU, researchers will collaborate on mapping mitochondrial physiology and medicine. The creation of such a unique well-coordinated network of senior researchers and young investigators will definitely put an added value to existing data and publications, will increase quality and validity of the research, will bring new possibilities of data sharing and data mining and will hopefully bring us to the era of more economical research by saving resources through standardised and harmnonised protocols, where the measuremnts will not be wasted due to lack of comparability. Lalic Nebojsa (2016).

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Publications

	Published	Reference
Pesta 2021 Front Endocrinol (Lausanne)	2021	Pesta D, Jelenik T, Zaharia OP, Bobrov P, Görgens S, Bódis K, Karusheva Y, Krako Jakovljevic N, Lalic NM, Markgraf DF, Burkart V, Müssig K, Knebel B, Kotzka J, Eckel J, Strassburger K, Szendroedi J, Roden M (2021) NDUFB6 polymorphism is associated with physical activity-mediated metabolic changes in type 2 diabetes. https://doi.org/10.3389/fendo.2021.693683
Krako Jakovljevic 2021 Int J Mol Sci	2021	Krako Jakovljevic N, Pavlovic K, Jotic A, Lalic K, Stoiljkovic M, Lukic L, Milicic T, Macesic M, Stanarcic Gajovic J, Lalic NM (2021) Targeting mitochondria in diabetes. Int J Mol Sci 22:6642.
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Zujovic 2019 MitoFit Preprint Arch EA	2019	Zujovic Tijana, Krako Jakovljevic N, Pavlovic K, Markovic I, Lalic NM (2019) Palmitate treated human hepatocellular carcinoma HuH7 cells require higher digitonin concentration for plasma membrane permeabilization. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0003

Abstracts

	Published	Reference
Ivanovic 2022 Abstract Bioblast	2022	P13. Ivanovic Tijana, Krako Jakovljevic N, Pavlovic K, Ciric D, Kravic-Stevovic T, Markovic I, Lalic NM (2022) Relationship of insulin resistance and mitochondria-associated endoplasmic reticulum membranes MAM in an in vitro lipotoxicity model. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Pavlovic 2022 Abstract Bioblast	2022	P15. Pavlovic Kasja, Krako Jakovljevic N, Isakovic AM, Ivanovic T, Markovic I, Lalic NM (2022) Effects of metformin on mitochondrial function in skeletal muscle cells: differences between therapeutic and suprapharmacological concentrations. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Lalic 2020 MiP2020	2020
Pavlovic 2019 MiP2019	2019	Effects of therapeutic metformin concentration on mitochondria in muscle cells.
Zujovic 2019 MiP2019	2019	Cell membrane permeabilization: digitonin optimization pitfalls.
Krako Jakovljevic 2019 MiP2019	2019	Lower insulin sensitivity differently affects mitochondrial coupling in liver and muscle cells.
Lalic 2109 MiP2019	2019	Pathophysiology of type 2 diabetes and mitochondrial dysfunction: possible therapeutic implications.
Pavlovic 2017 MITOEAGLE Obergurgl	2017	Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.