Difference between revisions of "Malate-aspartate shuttle"
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Revision as of 12:23, 17 May 2016
- high-resolution terminology - matching measurements at high-resolution
Malate-aspartate shuttle
Description
The malate-aspartate shuttle involves the glutamate-aspartate carrier and the 2-oxoglutarate carrier exchanging malate2- for 2-oxoglutarate2-. Cytosolic and mitochondrial malate dehydrogenase and transaminase complete the shuttle for the transport of cytosolic NADH into the mitochondrial matrix. It is most important in heart, liver and kidney.
Reference: Gnaiger 2012 MitoPathways
MitoPedia methods: Respirometry
MitoPedia topics: Enzyme
