Difference between revisions of "MitoKit-CII/Malonate-nv"
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|abbr=Mna(p) | |abbr=Mna(p) | ||
|description='''NV161 (diacetoxymethyl malonate)''', is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing malonate in the intracellular space. | |description='''NV161 (diacetoxymethyl malonate)''', is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing malonate in the intracellular space. | ||
|info=[[ | |info=[[MitoKit-CII]], [[MitoFit-CII|MitoPedia:MitoFit-CII]], [[Ehinger 2016 Nat Commun]] | ||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Medium | |mitopedia topic=Medium | ||
}} | }} | ||
* For preparation of MitoFit-CII, see [[ | * For preparation of MitoFit-CII, see [[MitoKit-CII]]. | ||
Revision as of 11:33, 25 March 2019
- high-resolution terminology - matching measurements at high-resolution
MitoKit-CII/Malonate-nv
Description
NV161 (diacetoxymethyl malonate), is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing malonate in the intracellular space.
Abbreviation: Mna(p)
Reference: MitoKit-CII, MitoPedia:MitoFit-CII, Ehinger 2016 Nat Commun
MitoPedia topics:
Media for respirometry
- For preparation of MitoFit-CII, see MitoKit-CII.
