Difference between revisions of "MitoKit-CII/Malonate-nv"
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{{MitoPedia | {{MitoPedia | ||
|abbr=Mna(p) Β | |abbr=Mna(p) Β | ||
|description='''NV161 (diacetoxymethyl malonate) | |description='''NV161/MitoKit-CII''' (diacetoxymethyl malonate) is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing malonate in the intracellular space. | ||
|info=[[MitoKit-CII]], [[MitoKit-CII MitoPedia]], [[Ehinger 2016 Nat Commun]] | |info=[[MitoKit-CII]], [[MitoKit-CII MitoPedia]], [[Ehinger 2016 Nat Commun]] | ||
}} | }} |
Revision as of 17:16, 28 March 2019
Description
NV161/MitoKit-CII (diacetoxymethyl malonate) is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing malonate in the intracellular space.
Abbreviation: Mna(p)
Reference: MitoKit-CII, MitoKit-CII MitoPedia, Ehinger 2016 Nat Commun
MitoPedia topics:
Media for respirometry
- For preparation of MitoFit-CII, see MitoKit-CII.