|
|
| (8 intermediate revisions by 4 users not shown) |
| Line 1: |
Line 1: |
| {{OROBOROS_header_page_name}}
| | #REDIRECT [[Oroboros O2k]] |
| :::: <big>'''[[Oxygraph-2k |OROBOROS Oxygraph-2k]] - unique for high-resolution respirometry (HRR)'''</big>
| |
| ::::::::::: <big>'''O2k - tested and trusted'''</big>
| |
| [[File:OROBOROS-Concept.jpg|right|300px|link=O2k high-resolution respirometry |HRR]]
| |
| __TOC__
| |
| | |
| == The O2k for high-resolution respirometry ==
| |
| [[Image:O2k-Fluorometer.JPG|left|120px|link=http://wiki.oroboros.at/index.php/Oxygraph-2k |O2k]]
| |
| | |
| The OROBOROS Oxygraph-2k provides a unique high-resolution approach for the monitoring of cellular and mitochondrial respiratory function: [[high-resolution respirometry |high-resolution respirometry (HRR)]]. Considering mitochondria as the powerhouses of the cell, HRR introduced the concept of [[cell ergometry]]. Are your cells [[MitoFit]]?
| |
| | |
| HRR is applied [[O2k-Network |world-wide]] in areas ranging from fundamental bioenergetics to the analysis of mitochondrial and metabolic diseases, advancing the rapidly growing field of preventive mitochondrial medicine. Mitochondrial fitness needs to be monitored in a variety of age-related health risks, including cardiovascular and degenerative diseases, such as type 2 diabetes, neurodegenerative diseases (Alzheimer’s, Parkinson’s, Huntington’s), and several types of cancer.
| |
| | |
| | |
| | |
| [[File:OROBOROS MitoFit-Lab.jpg|left|240px|link=http://wiki.oroboros.at/index.php/OROBOROS_INSTRUMENTS |OROBOROS]]
| |
| HRR by the OROBOROS O2k is based on a radically different systems approach to polarographic measurement of oxygen dynamics. HRR rests on several tightly connected instrumental features and concepts integrated by the DatLab software, providing real-time display of oxygen concentration and respiration ([[oxygen flux]]). The mechanics, critical selection of materials, and state-of-the-art electronics provide the basis of signal stability of an optimized [[polarographic oxygen sensor]], in an electronically controlled thermal environment with high temperature stability. Calibrations and instrumental controls follow standard operating procedures, with highly automatic real-time analysis by the DatLab software. Scientific support is complementary to the approach of HRR.
| |
| | |
| | |
| | |
| == From the O2k to the Power-O2k ==
| |
| [[Image:Power-O2k.png|left|120px|link=http://wiki.oroboros.at/index.php/Power-O2k|Power-O2k]]
| |
| Multiple O2k-units are offered as a ‘Power-O2k System’ for HRR combined with high-throughput - at high output.
| |
| | |
| :: ''More details? Consult'' [[Power-O2k]]
| |
| | |
| | |
| == Navigate to some pages ==
| |
| | |
| === The O2k concept ===
| |
| [[Image:Oxygraph-2k-Concept.jpg|250px|right|thumb|link=http://wiki.oroboros.at/index.php/Oxygraph-2k|Oxygraph-2k]]
| |
| [[Image:O2k-Info.png|left|150px|link=http://wiki.oroboros.at/index.php/OROBOROS_O2k-Catalogue|O2k-Catalogue]]
| |
| | |
| | |
| | |
| :::: <big>'''» [[Oxygraph-2k | OROBOROS Oxygraph-2k]]</big>: the modular system for [[high-resolution respirometry]]''' and mitochondrial physiology
| |
| | |
| | |
| Open Access in the spirit of [[Gentle Science]].
| |
| | |
| | |
| === [[OROBOROS O2k-Catalogue]] - a guided tour to the O2k ===
| |
| :: O2k is the acronym for the '''[[Oxygraph-2k]]''' and '''[[O2k-Fluorometer]]''' for [[high-resolution respirometry]].
| |
| | |
| [[Image:O2k-Manual.jpg|left|60px|link=O2k-Manual|O2k-Manual]]
| |
| [[Image:OROBOROS-Concept.jpg|right|500px|OROBOROS O2k-Info]]
| |
| | |
| | |
| === [[O2k-Manual]] ===
| |
| :: Instructions to application and service of the [[O2k-Core]], [[TIP2k]] and [[O2k-Catalogue:_O2k-MultiSensor|O2k-MultiSensor Modules]].
| |
| | |
| | |
| [[Image:O2k-Protocols.jpg|left|60px|link=O2k-Protocols|O2k-Protocols]]
| |
| === [[O2k-Protocols]] ===
| |
| :: O2k-Protocols are complementary to the O2k-Manual and O2k-Publications. Users are encouraged to get involved, contribute and share their expertise.
| |
| | |
| | |
| [[Image:O2k-Publications.jpg|left|60px|link=O2k-Publications: Topics|O2k-Publications in the MiPMap]]
| |
| === [[O2k-Publications]] ===
| |
| :: [[O2k-Publications: Topics |»{{#ask:[[Category:Publications]][[Instrument and method::Oxygraph-2k]] |format=count
| |
| }} O2k-Publications]] are part of the category '''[[Special:BrowseData/Publications|Publications]]''', providing a portal for sharing, disseminating and commenting relevant literature in mitochondrial physiology. Bioblast allows the “evolution” of a publication with space for open discussions and extensions of an otherwise static ‘paper’. This applies specifically to ''Methods and Materials'', ''Discussion'', and ''References'' sections, which may be limited by space in original publications.
| |
| | |
| | |
| [[Image:O2k-Network.png|left|60px|link=O2k-Network|O2k-Network]]
| |
| === [[O2k-Network]] ===
| |
| :: O2k-Network Labs from all over the world join to form the unique OROBOROS O2k-Network for high-resolution respirometry.
| |
| | |
| | |
| [[Image:O2k-Workshops.png|left|120px|link=OROBOROS_O2k-Workshops|O2k-Workshops]]
| |
| === [[OROBOROS O2k-Workshops |O2k-Workshops]] ===
| |
| :: Join us in the fast lane to high-resolution respirometry. While the OROBOROS O2k provides the instrumental basis for HRR, successful operation at high accuracy up to the limit of detection depends on a professional application by the technician, scientist or student. Participation in our hands-on introductory [[OROBOROS O2k-Workshops]] is recommended to save time and gain from the experience obtained over many years of application in various [[The world as a laboratory |settings]].
| |
| | |
| | |
| [[Image:The world as a laboratory.jpg|left|120px|link=http://wiki.oroboros.at/index.php/The_world_as_a_laboratory |The world as a laboratory]]
| |
| === [[The world as a laboratory]] ===
| |
| :: Science and adventure brings the OROBOROS-Team and the O2k to many and sometimes extreme parts of the world in international collaborations - [[The world as a laboratory]].
| |
| | |
| | |
| [[File:MiPNet.jpg|left|60px|link=http://wiki.oroboros.at/index.php/Mitochondr_Physiol_Network |Mitochondr Physiol Network]]
| |
| === [[Mitochondr Physiol Network]] ===
| |
| :: Mitochondrial Physiology Network - the OROBOROS on-line journal.
| |
