Rotenone: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=Rot | |abbr=Rot | ||
|description=(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; C<sub>23</sub>H<sub>22</sub>O<sub>6</sub>. Inhibitor of [[complex I]] via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI. | |description=(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; C<sub>23</sub>H<sub>22</sub>O<sub>6</sub>. Inhibitor of [[complex I]] via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI. See also [[S(Rot)|S<sub>(Rot)</sub>]]. | ||
|info=MiPNet11.09, MiPNet09.12, MiPNet12.15, MiPNet03.02 | |info=MiPNet11.09, MiPNet09.12, MiPNet12.15, MiPNet03.02 | ||
|type=Inhibitor ETS | |type=Inhibitor ETS |
Revision as of 10:37, 16 September 2010
Description
(2R,6aS,12aS)-1,2,6,6a,12,12a-hexahydro-2-isopropenyl-8,9 dimethoxychromeno[3,4-b]furo(2,3-h)chromen-6-on; C23H22O6. Inhibitor of complex I via inhibition of NADH oxidation.It inhibits the transfer of electrons from iron-sulfur centers in CI to ubiquinone via binding to the ubiquinone binding site of CI. See also S(Rot).
Abbreviation: Rot
Reference: MiPNet11.09, MiPNet09.12, MiPNet12.15, MiPNet03.02
Labels:
Enzyme: Complex I
HRR: Chemicals; Media"Chemicals; Media" is not in the list (Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, O2k-Spectrophotometer, O2k-Manual, O2k-Protocol, ...) of allowed values for the "Instrument and method" property.