Silva Ramos 2016 Biochim Biophys Acta: Difference between revisions
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|tissues=Fibroblast | |tissues=Fibroblast | ||
|preparations=Permeabilized cells | |preparations=Permeabilized cells | ||
|couplingstates=LEAK, OXPHOS, | |couplingstates=LEAK, OXPHOS, ET | ||
|pathways=S, Gp | |pathways=S, Gp | ||
|instruments=Oxygraph-2k | |instruments=Oxygraph-2k | ||
|additional=2016-11, | |additional=2016-11, | ||
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Latest revision as of 16:05, 13 November 2017
| Has title::Silva Ramos E, Larsson NG, Mourier A (2016) Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta 1857:1277-83. |
» [[Has info::PMID: 27060252]]
Was written by::Silva Ramos E, Was written by::Larsson NG, Was written by::Mourier A (Was published in year::2016) Was published in journal::Biochim Biophys Acta
Abstract: [[has abstract::Mitochondria are bioenergetic hotspots, producing the bulk of ATP by the oxidative phosphorylation process. Mitochondria are also structurally dynamic and undergo coordinated fusion and fission to maintain their function. Recent studies of the mitochondrial fusion machinery have provided new evidence in detailing their role in mitochondrial metabolism. Remarkably, mitofusin 2, in addition to its role in fusion, is important for maintaining coenzyme Q levels and may be an integral player in the mevalonate synthesis pathway. Here, we review the bioenergetic roles of mitochondrial dynamics and emphasize the importance of the in vitro growth conditions when evaluating mitochondrial respiration. This article is part of a Special Issue entitled 'EBEC 2016: 19th European Bioenergetics Conference, Riva del Garda, Italy, July 2-6, 2016,' edited by Prof. Paolo Bernardi.
Copyright © 2016. Published by Elsevier B.V.]] • Keywords: has publicationkeywords::Bioenergetics, has publicationkeywords::Coenzyme Q, has publicationkeywords::Mevalonate pathway, has publicationkeywords::Mitochondrial dynamics, has publicationkeywords::Mitofusin 2
• O2k-Network Lab: Was published by MiPNetLab::FR Bordeaux Devin A, Was published by MiPNetLab::DE Cologne Larsson NG
Labels: MiParea: MiP area::Respiration, MiP area::mt-Structure;fission;fusion, MiP area::Genetic knockout;overexpression
Organism: Organism::Mouse
Tissue;cell: tissue and cell::Fibroblast
Preparation: Preparation::Permeabilized cells
Coupling state: Coupling states::LEAK, Coupling states::OXPHOS, Coupling states::ET
Pathway: Pathways::S, Pathways::Gp
HRR: Instrument and method::Oxygraph-2k
