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  • ...ical Conference [http://www.mitoaction.org/laconference 2014 Mitochondrial Disease Clinical Conference] |info=[http://www.mitoaction.org/laconference 2014 Mitochondrial Disease Clinical Conference]
    740 bytes (82 words) - 11:23, 4 August 2014
  • ...faseb.org/SRC-HDAC/Home.aspx Histone Deacetylases and Sirtuins in Biology, Disease and Aging] ...faseb.org/SRC-HDAC/Home.aspx Histone Deacetylases and Sirtuins in Biology, Disease and Aging]
    782 bytes (107 words) - 16:14, 21 January 2015
  • |keyword=Liver disease, mitochondrial disease and diagnostics
    329 bytes (39 words) - 12:05, 8 February 2018
  • |title=2017 Sep 17-23. Global Mitochondrial Disease Awareness Week - [http://gmdaw.org/ GMDAW 2017] |abstract= Global Mitochondrial Disease Awareness Week 2017.
    1 KB (139 words) - 17:28, 5 September 2017
  • |title= '''Toronto CA''', 2017 Sep 29-30. MITO2017 Mitochondrial Disease Conference |info=[https://www.eventbrite.ca/e/mito2017-mitochondrial-disease-conference-registration-35602889200 MITO2017 webpage]
    2 KB (184 words) - 16:08, 22 August 2017
  • ...Medical Center, Department of Neurology, University of Kansas Alzheimerā€™s Disease Center |keyword=Alzheimerā€™s Disease, brain bioenergetics
    365 bytes (50 words) - 11:24, 4 October 2021
  • ...[http://www.journals.elsevier.com/neurobiology-of-disease/ Neurobiology of Disease]
    103 bytes (11 words) - 16:50, 22 March 2017
  • #REDIRECT [[United Mitochondrial Disease Foundation]]
    53 bytes (5 words) - 21:20, 19 June 2012
  • ...[http://www.springer.com/biomed/neuroscience/journal/11011 Metabolic Brain Disease]
    103 bytes (12 words) - 10:34, 11 December 2017
  • |Title=[http://www.aginganddisease.org/EN/2152-5250/home.shtml Aging and Disease]
    94 bytes (13 words) - 17:39, 8 January 2018
  • |Title=[http://www.nature.com/cddis/index.html Cell Death and Disease]
    83 bytes (13 words) - 18:01, 22 March 2017
  • ...epress.com/neuropsychiatric-disease-and-treatment-journal Neuropsychiatric Disease and Treatment]
    133 bytes (11 words) - 15:40, 29 January 2019
  • |keyword=huntingtonā€™s disease, parkinsonā€™s disease
    584 bytes (73 words) - 15:21, 27 April 2018
  • ...oisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinsonā€™s Disease. https://doi.org/10.26124/mitofit:2021-0004 ā€” ''2021-10-06 published in [ ...MitoFit_PD.pdf Mitochondrial homeostasis in cellular models of Parkinsonā€™s Disease]
    2 KB (284 words) - 08:43, 8 January 2023
  • |Title=[http://journals.sagepub.com/home/dvr Diabetes and Vascular Disease Research]
    97 bytes (13 words) - 11:43, 11 December 2017
  • |Title=[https://lipidworld.biomedcentral.com/ Lipids in Health and Disease]
    88 bytes (11 words) - 14:32, 25 April 2018
  • ...ournals.elsevier.com/bba-molecular-basis-of-disease BBA Molecular Basis of Disease]
    117 bytes (13 words) - 11:59, 2 November 2018
  • ...4<sup>th</sup> Regional Translational Research in Mitochondria, Aging, and Disease Symposium. ...oup, the Eberly College of Penn State University, the United Mitochondrial Disease Foundation
    904 bytes (114 words) - 08:35, 17 September 2014
  • |topics=Mitochondrial disease, Liver disease
    478 bytes (57 words) - 15:33, 2 April 2020
  • |Title=[http://dmm.biologists.org/ Disease Models and Mechanisms - Open Access]
    92 bytes (13 words) - 16:12, 18 October 2018
  • ...d method::Oxygraph-2k]] [[Diseases::Inherited]] OR [[Stress::Mitochondrial disease]] == O2k-Publications: Mitochondrial Disease; Degenerative Disease and Defect - Abstracts ==
    2 KB (206 words) - 16:38, 13 January 2023
  • ...nnual Conference of the Prevention and Control of Cardiovascular Metabolic Disease. ...nnual Conference of the Prevention and Control of Cardiovascular Metabolic Disease, Wuhan, CN; post-conference workshop '''[[MiPNet20.11_IOC102_Wuhan | 102nd
    2 KB (197 words) - 13:23, 23 January 2019
  • ...4-06. Mitochondrial Medicine - Developing New Treatments for Mitochondrial Disease, [https://registration.hinxton.wellcome.ac.uk/events/item.aspx?e=572 Mitoch ...tract=Mitochondrial Medicine - Developing New Treatments for Mitochondrial Disease, [https://registration.hinxton.wellcome.ac.uk/events/item.aspx?e=572 Mitoch
    739 bytes (87 words) - 13:15, 2 May 2016
  • ...ndrial-targeting Targeting Mitochondrial Dysfunction & Toxicity - Treating Disease and Improving Drug Safety]. ...ndrial-targeting Targeting Mitochondrial Dysfunction & Toxicity - Treating Disease and Improving Drug Safety].
    721 bytes (81 words) - 11:31, 4 August 2014
  • ...ata of mitochondrial function in cell lines as models of neurodegenerative disease. ...refore, mitochondrial dysfunction has been implicated in neurodegenerative disease and has been a focus point for research worldwide.
    2 KB (239 words) - 08:09, 13 September 2018
  • ...rformance in patients living with diabetic and non-diabetic chronic kidney disease ...ported and performance-based fatigue in persons living with chronic kidney disease
    2 KB (209 words) - 16:17, 3 November 2022
  • ...xygraph-2k]] [[Injury and adaptation::Mitochondrial Disease; Degenerative Disease and Defect]] ...xygraph-2k]] [[Injury and adaptation::Mitochondrial Disease; Degenerative Disease and Defect]]
    873 bytes (112 words) - 14:45, 10 April 2017
  • ...hondrial dysfunction as a cause or consequence of toxicity in Huntington's disease. Mech Ageing Dev 161:181-97. https://doi.org/10.1016/j.mad.2016.09.003 ...essing mitochondrial dysfunction as a cause or consequence of Huntington's disease.
    2 KB (236 words) - 11:01, 22 March 2023
  • ...Innsbruck AT |Mito Xmas Meeting 2016. Mitochondrial function in health and disease]].''' |abstract=Mitochondrial function in health and disease. Ā» [[Mito Xmas Meeting 2016 Innsbruck AT]].
    471 bytes (60 words) - 06:53, 13 June 2019
  • ...n BH, Naviaux RK (2008) The in-depth evaluation of suspected mitochondrial disease. Mol Genet Metab 94:16-37. ...challenge of evaluating patients of all ages with suspected mitochondrial disease.
    2 KB (270 words) - 17:18, 19 February 2018
  • |title=Middleton P, Vergis N (2021) Mitochondrial dysfunction and liver disease: role, relevance, and potential for therapeutic modulation. Therap Adv Gast ...n new therapeutic avenues in the management of patients with chronic liver disease.
    2 KB (207 words) - 12:20, 11 November 2023
  • Director, Alzheimer's Disease Center Director, Neurodegenerative Disease Program
    571 bytes (70 words) - 11:01, 17 March 2020
  • ...urlong LI (2018) comoRbidity: an R package for the systematic analysis of disease comorbidities. Bioinformatics 34:3228ā€“3230. ...m.nih.gov/29897411-comorbidity-an-r-package-for-the-systematic-analysis-of-disease-comorbidities/?from_term=comorbidity&from_pos=4 PMID: 29897411 Open Access]
    2 KB (298 words) - 00:35, 16 February 2020
  • ...ique can be used to investigate mitochondrial respiratory function for any disease in which patient-derived fibroblasts are available.
    2 KB (205 words) - 22:07, 23 August 2021
  • ...ary-disease-journal International journal of chronic obstructive pulmonary disease]
    181 bytes (14 words) - 13:36, 5 December 2018
  • ...Forbes JM, Thorburn DR (2018) Mitochondrial dysfunction in diabetic kidney disease. Nat Rev Nephrol 14:291-312. https://doi.org/10.1038/nrneph.2018.9 ...o be fully elucidated. Mitochondrial dysfunction is associated with kidney disease in nondiabetic contexts, and increasing evidence suggests that dysfunctiona
    2 KB (247 words) - 20:08, 14 September 2023
  • |keyword=Stress, Parkinson's Disease, Apoptosis, Mitochondrial Signalling |keywords=Stress; parkinson's disease; apoptosis
    736 bytes (96 words) - 13:50, 15 September 2021
  • |institution=Center for Mitochondrial Disease
    153 bytes (18 words) - 13:24, 21 August 2014
  • ...cts compared to acute mitochondrial dysfunction. The risk for developing a disease may be quantified in terms of a stress response, rather than a static patho
    794 bytes (104 words) - 16:32, 4 October 2011
  • ...energy metabolism or free-radical generation, or specific interactions of disease-related proteins with mitochondria, hold great promise.
    1 KB (140 words) - 09:33, 12 April 2022
  • ...Jul 15-18. 2nd Mitochondria Conference from Basic Biology to Mechanisms of Disease #Mito23 |authors=Basic Biology to Mechanisms of Disease
    1,002 bytes (110 words) - 09:40, 24 November 2022
  • ...zations involved in mitochondrial disease. Mitochondrial disease is a rare disease with a limited number of patients per country. The national patient organiz
    1 KB (155 words) - 10:40, 11 April 2017
  • == Alzheimer's disease == == Parkinson's disease ==
    1 KB (170 words) - 14:53, 29 November 2016
  • ...cytokines reveal sex differences in cerebellar mitochondria in Parkinsonā€™s disease and controls. ...ing and inflammation - A central role for mitochondria in brain health and disease. Ageing Res Rev 21:30ā€“42.
    1 KB (175 words) - 16:39, 1 October 2019
  • ...ndrial-targeting Targeting Mitochondrial Dysfunction & Toxicity - Treating Disease and Improving Drug Safety]. ...ndrial-targeting Targeting Mitochondrial Dysfunction & Toxicity - Treating Disease and Improving Drug Safety].
    901 bytes (100 words) - 11:15, 22 January 2015
  • |title='''Hinxton UK''', 2019 Dec 11-13. Mitochondrial Medicine - From disease mechanisms to therapeutic development |abstract= Mitochondrial Medicine - From disease mechanisms to therapeutic development, Hinxton, Unite Kingdom, 2019
    2 KB (279 words) - 11:48, 30 September 2019
  • |keyword=Respiratory OXPHOS disease == The Mitochondrial Disease Sequence Data Resource ==
    1 KB (206 words) - 14:04, 23 April 2024
  • ...f differential expression of mitochondrial-shaping proteins in parkinson's disease. Antioxidants (Basel) pii:e1. ...ng proteins to modifications of crucial cellular pathways affected in this disease.
    3 KB (412 words) - 12:01, 18 January 2019
  • ...igins-of-health-and-disease Journal of Developmental Origins of Health and Disease]
    171 bytes (17 words) - 16:49, 23 July 2018
  • ...27 - October 01. EMBO-FEBS Lecture Course 'Mitochondria in life, death and disease'. |authors=Mitochondria in life, death and disease
    1 KB (174 words) - 11:46, 2 February 2022
  • ...[http://www.hindawi.com/journals/ijad/contents/ The Journal of Alzheimer's Disease]}}
    102 bytes (14 words) - 17:36, 22 March 2017
  • Mitochondrial quality control signaling in Parkinsonā€™s disease models. ...sease mechanisms and to uncover novel pharmacological approaches to tackle disease progression.
    2 KB (259 words) - 13:37, 27 March 2018
  • ...in a mitochondrial DNA energy production gene can result in a neurological disease.
    1 KB (160 words) - 16:19, 13 September 2023
  • ...2019 Sep 24-28. EMBO-FEBS Lecture Course 'Mitochondria in life, death and disease'. |authors=Mitochondria in life, death and disease
    2 KB (176 words) - 11:18, 1 April 2019
  • ...ochondrial coupling defect in ''MFN2''-related Charcot-Marie-Tooth type 2A disease. Neurogenetics 11:127-33. ...anslocase (ANT) and uncoupling proteins from eight other patients with the disease. The mitochondrial uncoupling was associated with a higher respiratory rate
    2 KB (235 words) - 12:38, 16 February 2018
  • ...UK''', 2017 Mar 27-29. ROS and Mitochondria in Nervous System Function and Disease |abstract= ROS and Mitochondria in Nervous System Function and Disease, London, United Kingdom
    1 KB (159 words) - 10:06, 21 April 2017
  • ...ou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-2 ...ve factor against NAFLD. HBx may function as a risk factor for fatty liver disease, based on the findings of the present functional study; however, further st
    2 KB (329 words) - 16:42, 19 July 2022
  • ...chondrial respiratory function in peripheral blood cells from Huntingtonā€™s disease patients. Mov Disord doi:10.1002/mdc3.12308. ...on in 2 types of peripheral blood cells from 14 patients with Huntingtonā€™s disease and 21 control subjects. Several hypotheses were predefined, including impa
    3 KB (365 words) - 23:27, 29 February 2020
  • ...(2012) Mitochondrial dysfunction - a pharmacological target in Alzheimer's disease. Mol Neurobiol 46:136-50. ...ies are needed that focus on therapeutic strategies starting before severe disease progress.
    2 KB (272 words) - 07:53, 21 February 2020
  • ...ika E, Ischiropoulos H, Bakalar D, Blendy JA, Gasser DL (2012) Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 ( ...substantia nigra, implicating a pathology similar to sporadic Parkinson's disease (PD).
    1 KB (204 words) - 13:13, 20 March 2015
  • Cardiovascular and Metabolic Disease Center |keyword=Mitochondria Physiology, Heart Disease, Metabolic Syndrome
    815 bytes (113 words) - 14:09, 12 May 2019
  • |title=Itkis YS (2010) Respirometry application in Leigh disease diagnostic and treatment. MiPNet15.10. ...scles and in a wide variety of tissues. The clinical manifestation of this disease is extremely heterogeneous. It depends on a severity of oxidative phosphory
    2 KB (290 words) - 22:38, 16 March 2019
  • ...are discussed. We have interpreted the scientific literature and for each disease, we provide the reader with our best advice regarding the optimal type and
    2 KB (255 words) - 22:07, 1 June 2022
  • Mitochondrial function in exercise training and disease.
    276 bytes (32 words) - 13:58, 27 August 2014
  • ...017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23. ...nerative disease, particularly in populations most at risk for Alzheimer's disease in which stores are often depleted through mitochondrial dysfunction and el
    3 KB (338 words) - 17:48, 20 December 2017
  • ...Turnbull DM, Taylor RW (2017) The genetics and pathology of mitochondrial disease. J Pathol 241:236-50. https://doi.org/10.1002/path.4809 ...iew focuses on the current genetic landscape associated with mitochondrial disease, before focusing on advances in studying associated mitochondrial pathology
    2 KB (316 words) - 07:19, 14 October 2023
  • ...eabilized fibers from patients with coronary heart disease versus valvular disease. Mol Cell Biochem 379:229-34. ...r an early impairment of complex I supported respiration in ischemic heart disease, as previously demonstrated in the setting of experimental ischemia/reperfu
    2 KB (291 words) - 17:10, 19 February 2018
  • ...mov T (2017) Stable isotope-based flux studies in nonalcoholic fatty liver disease. Pharmacol Ther 181:22-33. ...provide new insights into the understanding of NAFLD pathogenesis and the disease progression. This review focuses mainly on the utilization of mass spectrom
    2 KB (236 words) - 16:46, 27 March 2018
  • ...nto H, Machado MV (2009) Uncoupling proteins and non-alcoholic fatty liver disease. J Hepatol 50:857-60. https://doi.org/10.1016/j.jhep.2009.02.019 ...cro-inflammation [3ā€“5]. In fact, NAFLD has been considered a mitochondrial disease [6,7].
    1 KB (175 words) - 22:49, 23 April 2023
  • ...gracz JE (2018) Mitochondrial dysfunction is a key determinant of the rare disease lymphangioleiomyomatosis and provides a novel therapeutic target. Oncogene ...decline. To identify new therapeutic strategies for this crippling orphan disease, we have performed array based and metabolic molecular analysis on patient-
    2 KB (222 words) - 12:32, 9 August 2019
  • ...s rather than in vitro studies or studies in animal models of neurological disease. In particular, the reasons why the outcomes of clinical trials supplementi
    1 KB (198 words) - 12:28, 9 November 2023
  • ...hen L, Yang Y, Fang H, Lyu J (2020) Systematic analysis of a mitochondrial disease-causing ND6 mutation in mitochondrial deficiency. Mol Genet Genomic Med 8:e ...t 16 years, emerging evidence suggests that mutant loads of m.14487T>C and disease phenotype are not closely correlated.
    2 KB (336 words) - 04:31, 21 November 2023
  • ...phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease. Aging (Albany NY) 2:170-6. ...other phosphatases, operate at the nexus between sarcopenia and metabolic disease.
    2 KB (268 words) - 12:45, 19 March 2015
  • ...oisoi N (2021) Mitochondrial homeostasis in cellular models of Parkinsonā€™s Disease. Bioenerg Commun 2021.2. https://doi.org/10.26124/bec:2021-0002 ...mitochondrial function parameters relative to factors that may potentiate disease progression.
    3 KB (364 words) - 16:43, 21 January 2024
  • ...maintain a satisfactory SpO2 during exercise in subjects with chronic lung disease (18 were diagnosed with COPD, and 3 with pulmonary fibrosis).
    928 bytes (125 words) - 23:13, 15 July 2022
  • ...tion is Canadaā€™s only not-for-profit organization focused on mitochondrial disease. Since its founding in 2010, MitoCanada has dedicated over $1 million to fu ...Foundation is committed to ensuring that those who live with mitochondrial disease are able to enjoy the best possible quality of life until there is a cure.
    3 KB (358 words) - 10:59, 4 January 2024
  • ...spiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83. ...les (aggregates of tau) in the brain, but the underlying mechanisms of the disease are still partially unclear. A growing body of evidence supports mitochondr
    2 KB (237 words) - 14:09, 22 August 2019
  • ...KW, Ren G, Mathews ST (2018) Potential role of coenzyme Q10 in health and disease conditions. Nutrition and Dietary Supplements 10:1-11. https://doi.org/10.2 |info=[https://www.dovepress.com/potential-role-of-coenzyme-q10-in-health-and-disease-conditions-peer-reviewed-fulltext-article-NDS Open Access]
    2 KB (286 words) - 16:28, 15 April 2023
  • ...rosidase deficiency and mitochondrial impairment in experimental Parkinson disease. J Neurol Sci 356:129-36. ...in the glucocerebrosidase gene (GBA) have been associated with Parkinson's disease (PD) and GBA mutations are now considered the most important genetic vulner
    2 KB (293 words) - 10:04, 23 February 2016
  • ...ctivation is an NAD<sup>+</sup>-sensitive mechanism contributing to kidney disease.
    2 KB (284 words) - 15:41, 19 December 2023
  • ...us infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS Genet 16:e1008604. ...n exacerbate mitochondrial dysfunction in a genetic model of mitochondrial disease.
    2 KB (278 words) - 17:20, 11 March 2020
  • ...'', 2019 Feb 27- Mar 02. Mitochondria: From Basic Biology to Mechanisms of Disease Conference |abstract= Mitochondria: From Basic Biology to Mechanisms of Disease Conference, Nassau, Bahamas, 2019
    1 KB (140 words) - 16:42, 30 November 2018
  • ...olecules that are currently being developed for treatment of mitochondrial disease. |injuries=Mitochondrial disease
    2 KB (238 words) - 14:36, 27 March 2018
  • ...czepanowska J (2023) In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts. https://doi.org/10.1016/j.bba ...tion. This may be helpful in the deciphering key pathomechanisms of the PD disease.
    2 KB (307 words) - 16:16, 20 June 2023
  • ...avis RL, Kumar KR (2021) Targeting mitochondrial impairment in Parkinson's disease: challenges and opportunities. Front Cell Dev Biol 8:615461. https://doi.or ...effective novel therapy targeting mitochondrial dysfunction in Parkinson's disease.
    2 KB (303 words) - 17:45, 5 October 2023
  • ...spiratory chain dysfunction-a hallmark pathology of idiopathic Parkinson's disease? Front Cell Dev Biol 10:874596. https://doi.org/10.3389/fcell.2022.874596 ...of the mitochondrial respiratory chain (MRC), has been associated with the disease. However, after decades of research in this field, the pervasiveness and an
    1 KB (199 words) - 11:43, 11 November 2023
  • ...e applications of this knowledge in the treatment of patients with cardiac disease.
    2 KB (215 words) - 16:48, 27 March 2018
  • ...pronounced alterations of these parameters may herald a progression of the disease toward irreversible septic shock.
    2 KB (305 words) - 17:29, 8 March 2021
  • ...ial bioenergetics in the metabolic myopathy accompanying peripheral artery disease. https://doi.org/10.3389/fphys.2017.00141 |abstract=Peripheral artery disease (PAD) is a serious but relatively underdiagnosed and undertreated clinical
    2 KB (277 words) - 15:44, 4 January 2023
  • ...ES''', 2021 Sep 21-24. EMBO Workshop: Mitochondrial homeostasis and human disease |abstract= EMBO Workshop: Mitochondrial homeostasis and human disease, Girona, ES, 2021
    1 KB (150 words) - 12:03, 9 June 2021
  • ...Overall, CHCHD10<sup>S55L</sup> mice recapitulate crucial aspects of human disease and reveal a novel toxic gain-of-function mechanism through maladaptive mtI
    2 KB (317 words) - 11:32, 16 August 2019
  • ...esults regarding their clinical utility. Treatment of commonly encountered disease of acute care such as sepsis, trauma, and poisoning often relies on clinica
    2 KB (252 words) - 23:26, 29 February 2020
  • ...x I deficiency in ''GDAP1''-related autosomal dominant Charcot-Marie-Tooth disease (CMT2K). Neurogenetics 10:145-50. ...ease (CMT4A), have also been associated with CMT2K, a dominant form of the disease. The three CMT2K patients we studied carried a novel dominant ''GDAP1'' mut
    2 KB (246 words) - 12:37, 16 February 2018
  • |title=Elhassan YS, Philp AA, Lavery GG (2017) Targeting NAD+ in metabolic disease; new insights into an old molecule. J Endocr Soc 1:816ā€“35. ...://academic.oup.com/jes/article/1/7/816/3827720/Targeting-NAD-in-Metabolic-Disease-New-Insights Open Access]
    2 KB (208 words) - 18:25, 20 March 2018
  • |title=ADFLIM in AD research ā€“imaging mitochondrial function in AlzheimerĀ“s disease ...imbalance in the brain, being one trigger of neuronal death in AlzheimerĀ“s disease.
    2 KB (300 words) - 15:38, 23 January 2019
  • ...priate therapy, and on the other hand, for the respective prognosis of the disease. However, particularly at the onset of symptoms, it is difficult to precise ...tisystem atrophy, Neurochemical diagnosis, Parkinson dementia, Parkinson disease, Progressive supranuclear palsy
    2 KB (299 words) - 14:40, 20 March 2015
  • |title=High-resolution respirometry for the diagnosis of mitochondrial disease. |injuries=Mitochondrial disease
    1 KB (139 words) - 15:41, 2 April 2020
  • |title=Chan DC (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125:1241-52. ...s (fusion and fission) of these organelles is important in development and disease.
    1 KB (139 words) - 18:23, 16 January 2021
  • ...ic treatments are available for some extremely rare forms of mitochondrial disease, but the majority of cases lack curative treatments, and the mainstay of tr
    2 KB (276 words) - 12:28, 15 October 2023
  • |institution=Cardiovascular and Metabolic Disease Center (CMDC)
    304 bytes (35 words) - 15:44, 13 February 2018

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