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A list of all pages that have property "Description" with value "'''PGMSGp''': [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]]". Since there have been only a few results, also nearby values are displayed.

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  • Overfitting  + ('''Overfitting''' in statistics is the act'''Overfitting''' in statistics is the act of mistaking noise for a signal. Overfitting makes a model look ‘’better’’ on paper but perform ‘’worse’’ in the real world. This may make it easier to get the model published in an academic journal or to sell to a client, crowding out more honest models from the marketplace. But if the model is fitting noise, it has the potential to hurt the science (quoted from [[Silver 2012 Penguin Press]]).nguin Press]]).)
  • Overlay of plots - DatLab  + ('''Overlay of plots''' is defined in DatLa'''Overlay of plots''' is defined in DatLab as selection of graph layouts showing identical plots from the two O2k-chambers in each graph. Overlay of plots is selected in [[Graph layout - DatLab |Graph layout]]. Superimposed traces of flux/flow from chambers A and B are then shown in Graph 1, and of concentration in chambers A and B in Graph 2.</br></br>There are basically two ways to superimpose traces recorded in different experiments: Export of the graphics via windows metafile or export of the data to e.g. a spreadsheet program.</br></br>If you export via wmf you also can manipulate the graphics but then usually the lines are broken up in different segments. This can be done in various programs like MS Word, Open Office Draw and even in MSPower Point, though this maybe is the worst program to do this. It is better to manipulate them in a proper program like OO Draw, convert it to an unchangeable picture and then import it to a presentation graphics. Anyway, when you import directly to Power point (or other programs), make sure not to import it as a "picture" but as a metafile. Also in some programs you might afterwards have to "break" it up, or accept a "conversion to a MS Draw object" or other similar linguistic inventions of the software gurus. For this option we suggest to do as much as possible directly in DatLab (setting colors, line widths, ..) using the options in "Plots"/"select plots" and "graph"/"options". </br></br>The “hardcore“ option is to export the data and import it into e.g. a spreadsheet program (MS Excel , OOCalc). It takes longer to have a simple overlay but gives you far less problems later and its easier to make changes later. To do this you can export your dataset "Export"/"Data to Textfile" and then go from there."Data to Textfile" and then go from there.)
  • Oxalomalic acid  + ('''Oxalomalic acid''' is an inhibitor of a'''Oxalomalic acid''' is an inhibitor of aconitase (and of cytoplasmic NADP-dependent isocitrate dehydrogenase). Aconitase mediates the isomerization of citrate to isocitrate as the first step in the [[TCA_cycle| TCA cycle]]. Oxalomalic acid has been used at 1 mM concentration and after 45 min of pre-incubation to inhibit aconitase in permeabilized rat Soleus muscle fibres, inhibiting the enzyme by 24% ([[Osiki 2016 FASEB J]]).[[Osiki 2016 FASEB J]]).)
  • Oxidative stress  + ('''Oxidative stress''' results from an imb'''Oxidative stress''' results from an imbalance between pro-oxidants and antioxidants shifting the equilibrium in favor of the pro-oxidants. This process can be due by an increment in pro-oxidants, by a depletion of antioxidant systems or both. Oxidative stress generates oxidative damage of proteins, lipids and DNA.dative damage of proteins, lipids and DNA.)
  • Oxoglutarate dehydrogenase  + ('''Oxoglutarate dehydrogenase''' (α-ketogl'''Oxoglutarate dehydrogenase''' (α-ketoglutarate dehydrogenase) is a highly regulated enzyme of the [[tricarboxylic acid cycle]]. It catalyses the conversion of oxoglutarate (alpha-ketoglutarate) to succinyl-CoA, reduces NAD<sup>+</sup> to [[NADH]] and thus links to [[Complex I]] in the Electron transfer-pathway. OgDH is activated by low Ca<sup>2+</sup> (<20 µM) but inactivated by high Ca<sup>2+</sup> (>100 µM). OgDH is an important source of ROS.y high Ca<sup>2+</sup> (>100 µM). OgDH is an important source of ROS.)
  • Oxygen flux  + ('''Oxygen flux''', ''J''<sub>O<su'''Oxygen flux''', ''J''<sub>O<sub>2</sub></sub>, is a [[specific quantity]]. Oxygen [[flux]] is [[oxygen flow]], ''I''<sub>O<sub>2</sub></sub> [mol·s<sup>-1</sup> per system] (an [[extensive quantity]]), divided by system size. Flux may be volume-specific (flow per volume [pmol·s<sup>-1</sup>·mL<sup>-1</sup>]), mass-specific (flow per mass [pmol·s<sup>-1</sup>·mg<sup>-1</sup>]), or marker-specific (flow per mtEU). Oxygen flux (''e.g.'', per body mass, or per cell volume) is distinguished from oxygen flow (per number of objects, such as cells), ''I''<sub>O<sub>2</sub></sub> [mol·s<sup>-1</sup>·x<sup>-1</sup>]. These are different forms of [[normalization of rate]].lization of rate]].)
  • Oxygen kinetics  + ('''Oxygen kinetics''' describes the depend'''Oxygen kinetics''' describes the dependence of respiration of isolated mitochondria or cells on oxygen partial pressure. Frequently, a strictly hyperbolic kinetics is observed, with two parameters, the oxygen pressure at half-maximum flux, ''p''<sub>50</sub>, and maximum flux, Jmax. The ''p''<sub>50</sub> is in the range of 0.2 to 0.8 kPa for cytochrome ''c'' oxidase, isolated mitochondria and small cells, strongly dependent on ''J''<sub>max</sub> and coupling state.lls, strongly dependent on ''J''<sub>max</sub> and coupling state.)
  • Oxygen pressure  + ('''Oxygen pressure''' or partial [[pressure]] of oxygen [kPa], related to oxygen concentration in solution by the [[oxygen solubility]], ''S''<sub>O2</sub> [µM/kPa].)
  • Ap5A  + ('''P1,P5-Di(adenosine-5')pentaphosphate (Ap5A)''' is an inhibitor of [[adenylate kinase]] (ADK), the enzyme which rephosphorylates AMP to ADP, consuming ATP (ATP + AMP ↔ 2 ADP).)
  • PGMSGp pathway control state  + ('''PGMSGp''': [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]] & [[Glycerophosphate]]. '''MitoPathway control state:''' NSGp '''SUIT protocol:''' [[SUIT-038]] This substrate combination supports convergent electron flow to the [[Q-junction]].)
 ('''PGMSGp''': [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]])
  • POS-Service Kit  + ('''POS-Service Kit''', in [[O2k-Accessory Box]] including all oxygen sensor service accessories for membrane mounting and service of the [[OroboPOS|POS]].)
  • PREreview  + ('''PREreview''' encourages scientists to p'''PREreview''' encourages scientists to post their scientific outputs as preprints. PREreview makes it easier to start and run a Preprint Journal Club, or integrate preprint review into conventional journal clubs. PREreview seeks to diversify peer review in the academic community by crowdsourcing pre-publication feedback to improve the quality of published scientific output, and to train early-career researchers (ECRs) in how to review others' scientific work. We want to facilitate a cultural shift in which every scientist posts, reads, and engages with preprints as standard practice in scholarly publishing. We see PREreview as a hub to support and nurture the growth of a community that openly exchanges timely, constructive feedback on emerging scientific outputs. We believe that by empowering ECRs through peer review training programs, thereby increasing the diversity of researchers involved in the peer review process, PREreview will help establish a healthier and more sustainable culture around research dissemination and evaluation. This project was born in April 2017 as a collaboration between Samantha Hindle and Daniela Saderi, scientists and [[ASAPbio]] Ambassadors, with help from Josh Nicholson, at the time working for [https://www.authorea.com/aboutus Authorea].ttps://www.authorea.com/aboutus Authorea].)
  • Packing\O2k-Box 1+2  + ('''Packing\O2k-Box 1+2''' for shipping the [[O2k-Core]]. O2k-WorldWide delivery, insurance and handling are included in the O2k-Core.)
  • PalM  + ('''PalM''': [[Palmitoylcarnitine]] & [[Malate]]. '''MitoPathway control state:''' [[ F | Fatty acid oxidation pathway control state]] '''SUIT protocols:''' [[SUIT-019]])
  • PalOctM  + ('''PalOctM''': [[Palmitoylcarnitine]] & [[Octanoylcarnitine]] & [[Malate]]. '''MitoPathway control state:''' [[ F | Fatty acid oxidation pathway control state]] '''SUIT protocols:''' [[SUIT-019]])
  • PalOctPGM  + ('''PalOctPGM''': [[Palmitoylcarnitine]] & [[Octanoylcarnitine]] & [[Pyruvate]] & [[Glutamate]] & [[Malate]]. '''MitoPathway control state:''' [[FN]] '''SUIT protocols:''' [[SUIT-019]])
  • PalOctPGMS  + ('''PalOctPGMS''': [[Palmitoylcarnitine]] & [[Octanoylcarnitine]] & [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]]. '''MitoPathway control state:''' [[FNS]] '''SUIT protocols:''' [[SUIT-019]])
  • PalOctPM  + ('''PalOctPM''': [[Palmitoylcarnitine]] & [[Octanoylcarnitine]] & [[Pyruvate]] & [[Malate]]. '''MitoPathway control state:''' [[FN]] '''SUIT protocols:''' [[SUIT-019]])
  • PalPGMSGp pathway control state  + ('''PalPGMSGp''': [[Palmitoylcarnitine]]'''PalPGMSGp''': [[Palmitoylcarnitine]] & [[Pyruvate]] & [[Glutamate]] & [[Malate]] & [[Succinate]] & [[Glycerophosphate]].</br></br>'''MitoPathway control state:''' FNSGp</br></br>'''SUIT protocol:''' [[SUIT-026]]</br></br>This substrate combination supports convergent electron flow to the [[Q-junction]].[[Q-junction]].)
  • Palmitate  + ('''Palmitate''' is a term for the salts an'''Palmitate''' is a term for the salts and esters of palmitic acid (CH<sub>3</sub>(CH<sub>2</sub>)<sub>14</sub>COOH). Palmitic acid is the first fatty acid produced during fatty acid synthesis and the precursor to longer fatty acids. Palmitate negatively feeds back on acetyl-CoA carboxylase (ACC), which is responsible for converting acetyl-CoA to malonyl-CoA, which in turn is used to add to the growing acyl chain, thus preventing further palmitate generation. In order to dissolve the water-insoluble sodium palmitate, [[Bovine serum albumine| BSA]] is needed to form the water-soluble compound called palmitate:BSA.[[Bovine serum albumine| BSA]] is needed to form the water-soluble compound called palmitate:BSA.)
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