Difference between revisions of "Template:Current week ecosystem agenda"

Revision as of 09:52, 20 November 2023

Oroboros declares solidarity against the Russian aggression-war in Ukraine and against all aggression-wars worldwide. - »More details

-» A future for Ukraine is the future of its science

2023 Week 47

Nov- 20 Mo

Do I need to change the filter set of the O2k-Fluo Smart-Module?

Because two different filter sets can be used with the blue Fluo-Sensors, filters should be changed according to the fluorophore that will be used. Extra filters are provided for replacement in case of damage.
- »O2k-Fluo Smart-Module manual« and »O2k-Fluo Smart-Module - Fluorescence dyes and settings«
- communicated by »Cardoso Luiza« and »Timon-Gomez Alba«

Nov- 21 Tu

Nov- 22 We

Nov- 23 Th

"Thoughtful design and execution of O2k experiments result in data that become a powerhouse for addressing many mitochondrial respiration research questions. "

Walsh MA, Musci RV, Jacobs RA, Hamilton KL (2023) A practical perspective on how to develop, implement, execute, and reproduce high-resolution respirometry experiments: The physiologist's guide to an Oroboros O2k »Bioblast link«

from the O2k-Network »US CO Colorado Springs Jacobs RA« and »US CO Fort Collins Hamilton K«

Nov- 24 Fr

Next Week

2023 Week 48

Nov- 27 Mo

Nov- 28 Tu

Protocols that SUIT your research question

Using Substrate-Uncoupler-Inhibitor-Titration protocols you can study mitochondrial respiratory control through a sequence of coupling and pathway control states induced by multiple titrations within a single experimental assay.
- »SUIT protocols« and »SUITbrowser«
- communicated by »Schmitt Sabine« and »Timon-Gomez Alba«

Nov- 29 We

Nov- 30 Th

Dec- 01 Fr World AIDS day

"We therefore hypothesized that the susceptibility to HIV-1 infection of FOXO1-inhibited resting T cells could be due to an increased cell metabolism. (...) Results obtained by high-resolution respirometry experiments of [human peripheral blood T cells] PBT (...) showed that [ROUTINE] respiration at the steady state was increased by [FOXO1 inhibitor] AS1842856."

Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M (2019) FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction. »Bioblast link«

from the O2k-Network »FR Paris Bouillaud F«

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 46
-*'''Nov- 13 Mo'''
-----
-*'''Nov- 14 Tu''' - World Diabetes Day
-:{|
-| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"Liver [mitochondria] (...) adapt to metabolic challenges by increasing FAO-derived mitochondrial respiration in OBES [obesity model] and NASH [non-alcoholic steatohepatitis model], but by increasing both FAO- and TCA-derived respiration in DIAB [diabetes model]."''' <br>
-* Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. [[Dewidar 2023 EBioMedicine|»Bioblast link«]]
-:from the O2k-Network »[[DE Duesseldorf Roden M]]« and »[[DE Cologne Pesta D]]«
-|}
-----
-*'''Nov- 15 We'''
-----
-*'''Nov- 16 Th''' - World Pancreatic Cancer Day
-:{|
-| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"To the advantage of PDAC [pancreatic ductal adenocarcinoma] patients, innovative and more effective therapeutics will be possible with a greater understanding of how pancreatic cancer cells control mitochondrial metabolism."''' <br>
-* Padinharayil H, Rai V, George A (2023) Mitochondrial metabolism in pancreatic ductal adenocarcinoma: from mechanism-based perspectives to therapy. [[Padinharayil 2023 Cancers (Basel)|»Bioblast link«]]
-|}
-----
-*'''Nov- 17 Fr'''
-----
-'''<big>Next Week</big>'''
 Week 47
@@ Line 50: / Line 25: @@
 ----
 *'''Nov- 24 Fr'''
+----
+'''<big>Next Week</big>'''
+Week 48
+*'''Nov- 27 Mo'''
+----
+*'''Nov- 28 Tu'''
+:{|
+| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
+|'''Protocols that SUIT your research question'''<br>
+Using '''S'''ubstrate-'''U'''ncoupler-'''I'''nhibitor-'''T'''itration protocols you can study mitochondrial respiratory control through a sequence of coupling and pathway control states induced by multiple titrations within a single experimental assay. <br>
+- »'''[https://wiki.oroboros.at/index.php/MitoPedia:_SUIT SUIT protocols]'''« and »'''[https://bioblast.at/index.php/SUITbrowser SUITbrowser]'''« <br>
+- communicated by »[[Schmitt Sabine]]« and »[[Timon-Gomez Alba]]«
+|}
+----
+*'''Nov- 29 We'''
+----
+*'''Nov- 30 Th'''
+----
+*'''Dec- 01 Fr'''  <span style="color:red">World AIDS day</span>
+:{|
+| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
+|'''"We therefore hypothesized that the susceptibility to HIV-1 infection of FOXO1-inhibited resting T cells could be due to an increased cell metabolism. (...) Results obtained by high-resolution respirometry experiments of [human peripheral blood T cells] PBT (...) showed that [ROUTINE] respiration at the steady state was increased by [FOXO1 inhibitor] AS1842856."''' <br>
+* Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M (2019) FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction.  [[Roux 2019 PLoS Pathog|»Bioblast link«]]
+:from the O2k-Network »[[FR Paris Bouillaud F]]«
+|}
 ----