Template:SUIT Rot Snv: Difference between revisions
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Rotenone inhibits [[Complex I]], thus inhibiting the [[TCA cycle]] in [[living cells]] with intact plasma membrane. In the presence of Succinate-nv (diacetoxymethyl succinate, MitoKit-CII), the intracellular release of succinate independent of the TCA | Rotenone inhibits [[Complex I]], thus inhibiting the [[TCA cycle]] in [[living cells]] with intact plasma membrane. In the presence of Succinate-nv (diacetoxymethyl succinate, MitoKit-CII), the intracellular release of succinate independent of the TCA cycle leads to stimulation of respiration. | ||
Latest revision as of 16:18, 1 July 2019
Rotenone inhibits Complex I, thus inhibiting the TCA cycle in living cells with intact plasma membrane. In the presence of Succinate-nv (diacetoxymethyl succinate, MitoKit-CII), the intracellular release of succinate independent of the TCA cycle leads to stimulation of respiration.
