Difference between revisions of "Tricarboxylic acid cycle"
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|abbr=TCA | |abbr=TCA | ||
|description=The '''tricarboxylic acid (TCA) cycle''' is a system of enzymes in the mitochondrial matrix (and [[succinate dehydrogenase]] in the inner mt-membrane) arranged in a cyclic metabolic structure, including dehydrogenases that converge in the NADH pool and [[succinate dehydrogenase]] for entry into the [[ETS]].ย [[Citrate synthase]] is a marker enzyme of the TCA cycle, at the gateway into the cycle from pyruvate via acteyl-CoA.ย Sections of TCA cycle are required for [[ฮฒ-oxidation]].ย [[Anaplerotic reactions]] fuel the TCA cycle with other intermediary metabolites.ย In the cell, the TCA cycle serves biosynthetic functions by metabolite export from the matrix into the cytosol. | |description=The '''tricarboxylic acid (TCA) cycle''' is a system of enzymes in the mitochondrial matrix (and [[succinate dehydrogenase]] in the inner mt-membrane) arranged in a cyclic metabolic structure, including dehydrogenases that converge in the NADH pool and [[succinate dehydrogenase]] for entry into the [[ETS]].ย [[Citrate synthase]] is a marker enzyme of the TCA cycle, at the gateway into the cycle from pyruvate via acteyl-CoA.ย Sections of TCA cycle are required for [[ฮฒ-oxidation]].ย [[Anaplerotic reactions]] fuel the TCA cycle with other intermediary metabolites.ย In the cell, the TCA cycle serves biosynthetic functions by metabolite export from the matrix into the cytosol. | ||
|info=[[MiPNet12.12]] | |info=[[MiPNet12.12]] | ||
|type=Enzyme | |||
}} | |||
{{MitoPedia topics | |||
|mitopedia topic=Enzyme | |||
|type=Enzyme | |type=Enzyme | ||
}} | }} | ||
{{Labeling | {{Labeling | ||
|discipline=Mitochondrial Physiology | |discipline=Mitochondrial Physiology | ||
|enzymes=TCA Cycle and Matrix Dehydrogenases, Complex II; Succinate Dehydrogenase, Marker Enzyme | |||
|topics=Substrate; Glucose; TCA Cycle | |topics=Substrate; Glucose; TCA Cycle | ||
| | |type=Enzyme | ||
}} | }} | ||
Revision as of 14:40, 9 March 2011
- high-resolution terminology - matching measurements at high-resolution
Tricarboxylic acid cycle
Description
The tricarboxylic acid (TCA) cycle is a system of enzymes in the mitochondrial matrix (and succinate dehydrogenase in the inner mt-membrane) arranged in a cyclic metabolic structure, including dehydrogenases that converge in the NADH pool and succinate dehydrogenase for entry into the ETS. Citrate synthase is a marker enzyme of the TCA cycle, at the gateway into the cycle from pyruvate via acteyl-CoA. Sections of TCA cycle are required for ฮฒ-oxidation. Anaplerotic reactions fuel the TCA cycle with other intermediary metabolites. In the cell, the TCA cycle serves biosynthetic functions by metabolite export from the matrix into the cytosol.
Abbreviation: TCA
Reference: MiPNet12.12
MitoPedia topics:
Enzyme
Labels:
Enzyme: TCA Cycle and Matrix Dehydrogenases"TCA Cycle and Matrix Dehydrogenases" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property., Complex II; Succinate Dehydrogenase"Complex II; Succinate Dehydrogenase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property., Marker Enzyme"Marker Enzyme" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property. Regulation: Substrate; Glucose; TCA Cycle"Substrate; Glucose; TCA Cycle" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
