ET capacity: Difference between revisions

Revision as of 15:29, 18 September 2010

high-resolution terminology - matching measurements at high-resolution

ET capacity

Description

[[Description::Respiratory electron transfer system capacity, E, of mitochondria in the experimentally induced non-coupled (fully uncoupled) state, in mitochondrial preparations with defined substrates, or in intact cells, by titration of an established uncoupler to optimum concentration at maximum flux. Non-coupled respiration yields an estimate of ETS capacity. In this state E, the mt-membrane potential is collapsed, which provides a reference state for flux control ratios and measurement of mt-membrane potential.]]

Abbreviation: E

Reference: MiPNet12.15, Gnaiger_2009_IJCBC

Labels:

Preparation: Intact Cell; Cultured; Primary, Isolated Mitochondria, Permeabilized Cell or Tissue; Homogenate

Regulation: Respiration; OXPHOS; ETS Capacity, Coupling; Membrane Potential

@@ Line 1: / Line 1: @@
 {{MitoPedia
-|abbr=State ''E''
+|abbr=''E''
-|description='''[[ETS|Respiratory electron transfer system]] capacity''' of mitochondria in the experimentally induced state of [[non-coupled respiration]] (fully uncoupled; state ''E''), obtained in intact cells or mitochondrial preparations with defined substrates, by titration of an established [[uncoupler]] up to optimum concentration at maximum flux.  Non-coupled respiration yields an estimate of ETS capacity.  In this state ''[[E]]'', the mt-membrane potential is collapsed, which provides a reference state for flux control ratios and for measurement of the mt-membrane potential.
+|description=Respiratory [[ETS|electron transfer system]] capacity, ''E'', of mitochondria in the experimentally induced [[non-coupled]] (fully uncoupled) state, in [[mitochondrial preparations]] with defined substrates, or in intact cells, by titration of an established [[uncoupler]] to optimum concentration at maximum flux. Non-coupled respiration yields an estimate of '''ETS capacity'''.  In this state ''E'', the [[mt-membrane potential]] is collapsed, which provides a reference state for [[flux control ratios]] and measurement of mt-membrane potential.
 |info=MiPNet12.15, Gnaiger_2009_IJCBC
 |type=Respiration
@@ Line 7: / Line 7: @@
 {{Labeling
 |discipline=Mitochondrial Physiology
+|preparations=Intact Cell; Cultured; Primary, Isolated Mitochondria, Permeabilized Cell or Tissue; Homogenate
+|topics=Respiration; OXPHOS; ETS Capacity, Coupling; Membrane Potential
 }}