E-L coupling efficiency: Difference between revisions
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* [[Gnaiger 1993 Hypoxia|Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109.]] | * [[Gnaiger 1993 Hypoxia|Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109.]] | ||
* [[Gnaiger 2012 MitoPathways]] | * [[Gnaiger 2012 MitoPathways]] | ||
* [[Uncoupler]] |
Revision as of 00:34, 18 April 2014
Description
The biochemical coupling efficiency is expressed as the E-L coupling control factor, ΔjE-L=(E-L)/E, which is 0.0 at zero coupling (L=E; LEAK=ETS capacity) and 1.0 at the limit of a fully coupled system (L=0). Compare with the thermodynamic efficiency of coupling between ATP production (DT phosphorylation) and oxygen consumption (ergodynamic efficiency).
Abbreviation: ΔjE-L
Reference: Flux control factor
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Gnaiger E (2014) Biochemical coupling efficiency: from 0 to <1. Mitochondr Physiol Network 2014-04-18. |
OROBOROS (2014) Mitochondr Physiol Network
Abstract: Zooming in on biochemical coupling efficiency.
• O2k-Network Lab: AT Innsbruck Gnaiger E
Labels:
Regulation: Coupling efficiency;uncoupling
Coupling state: LEAK, ETS"ETS" is not in the list (LEAK, ROUTINE, OXPHOS, ET) of allowed values for the "Coupling states" property.
HRR: Theory
Biochemical coupling efficiency: from 0 to <1
MitoPedia links
Coupling
Coupling control ratios
- E-L coupling control factor
- E-P coupling control factor
- E-R coupling control factor
- LEAK control ratio per E
- Phosphorylation system control ratio
- Respiratory acceptor control ratio
Relevant respiratory states
Basics
References
- Gnaiger E (1993) Nonequilibrium thermodynamics of energy transformations. Pure Appl Chem 65: 1983-2002.
- Gnaiger E (1993) Efficiency and power strategies under hypoxia. Is low efficiency at high glycolytic ATP production a paradox? In: Surviving Hypoxia: Mechanisms of Control and Adaptation. Hochachka PW, Lutz PL, Sick T, Rosenthal M, Van den Thillart G (eds) CRC Press, Boca Raton, Ann Arbor, London, Tokyo: 77-109.
- Gnaiger 2012 MitoPathways
- Uncoupler