Difference between revisions of "E-P control efficiency"
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{{MitoPedia | {{MitoPedia | ||
|abbr='' | |abbr=''Ex<sub>P</sub>/E'' | ||
|description=The '''''E-P'' coupling control factor | |description=The apparent '''ETS excess factor over ''P''''' (''E-P'' coupling control factor), ''Ex<sub>P</sub>/E'' = (''E-P'')/''E'', is an expression of the relative limitation of [[OXPHOS capacity]] by the capacity of the [[phosphorylation system]]. ''Ex<sub>P</sub>/E'' = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, ''P''=''E'', when the phosphorylation system does not exert any control over OXPHOS capacity. ''Ex<sub>P</sub>/E'' increases with increasing control of the phosphorylation system over OXPHOS capacity. ''Ex<sub>P</sub>/E'' = 1 at the limit of zero phosphorylation capacity. The [[OXPHOS]] state of mt-preparations is stimulated to [[ETS]] by [[uncoupler]] titration. | ||
|info=[[Flux control factor]] | |info=[[Flux control factor]] | ||
}} | }} | ||
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|mitopedia topic=Respiratory control ratio | |mitopedia topic=Respiratory control ratio | ||
}} | }} | ||
== | == Compare == | ||
* [[Phosphorylation system control ratio]] | |||
* ''More details:'' [[Biochemical coupling efficiency]] | * ''More details:'' [[Biochemical coupling efficiency]] | ||
Revision as of 12:58, 9 August 2014
- high-resolution terminology - matching measurements at high-resolution
E-P control efficiency
Description
The apparent ETS excess factor over P (E-P coupling control factor), ExP/E = (E-P)/E, is an expression of the relative limitation of OXPHOS capacity by the capacity of the phosphorylation system. ExP/E = 0.0 when OXPHOS is not limited by the phosphorylation system at zero ETS excess capacity, P=E, when the phosphorylation system does not exert any control over OXPHOS capacity. ExP/E increases with increasing control of the phosphorylation system over OXPHOS capacity. ExP/E = 1 at the limit of zero phosphorylation capacity. The OXPHOS state of mt-preparations is stimulated to ETS by uncoupler titration.
Abbreviation: ExP/E
Reference: Flux control factor
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory control ratio"Respiratory control ratio" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
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