Flux control ratio: Difference between revisions
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|abbr=''FCR'' | |abbr=''FCR'' | ||
|description='''Flux control ratios''' (''FCR''), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). ''FCR'' obtained from a single respirometric incubation (sequential protocol; [[SUIT protocol]]) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. ''FCR'' obtained from separate (parallel) protocols depend on determination of a common [[mitochondrial marker]]. | |description='''Flux control ratios''' (''FCR''), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). ''FCR'' obtained from a single respirometric incubation (sequential protocol; [[SUIT protocol]]) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. ''FCR'' obtained from separate (parallel) protocols depend on determination of a common [[mitochondrial marker]]. | ||
|info=[ | |info=[http://www.oroboros.at/?Gnaiger_2012_MitoPathways Gnaiger 2012 MitoPathways], [[Gnaiger 2009 Int J Biochem Cell Biol]], [[Pesta 2012 Methods Mol Biol]] | ||
|type=Respiration | |type=Respiration | ||
}} | }} | ||
Revision as of 18:11, 8 January 2013
- high-resolution terminology - matching measurements at high-resolution
Flux control ratio
Description
[[Description::Flux control ratios (FCR), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). FCR obtained from a single respirometric incubation (sequential protocol; SUIT protocol) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. FCR obtained from separate (parallel) protocols depend on determination of a common mitochondrial marker.]]
Abbreviation: Has abbr::''FCR''
Reference: [[Info::Gnaiger 2012 MitoPathways, Gnaiger 2009 Int J Biochem Cell Biol, Pesta 2012 Methods Mol Biol]]
MitoPedia methods:
Respirometry
MitoPedia topics:
MitoPedia topic::Respiratory state
