Flux control ratio

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Flux control ratio

Description

[[Description::Flux control ratios (FCR), are ratios of oxygen flux in different respiratory control states, normalized for maximum flux in a common reference state, to obtain theoretical lower and upper limits of 0.0 and 1.0 (0% and 100%). FCR obtained from a single respirometric incubation (sequential protocol; SUIT protocol) provide an internal normalization, expressing respiratory control independent of mitochondrial content and thus independent of a marker for mitochondrial amount. FCR obtained from separate (parallel) protocols depend on determination of a common mitochondrial marker.]]

Abbreviation: Has abbr::''FCR''

Reference: [[Info::MiPNet12.15, Gnaiger 2009 Int J Biochem Cell Biol, Pesta 2012 Methods Mol Biol]]


MitoPedia methods: Respirometry 


MitoPedia topics: MitoPedia topic::Respiratory state