L/E coupling-control ratio: Difference between revisions
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{{MitoPedia | {{MitoPedia | ||
|abbr=''L/E'' | |abbr=''L/E'' | ||
|description=The '''LEAK control ratio''' is an index of [[uncoupling]] or [[dyscoupling]] at constant | |description=The '''LEAK control ratio''', ''L/E'', is the flux ratio of [[LEAK respiration]] over [[ETS capacity]], as determined by measurement of oxygen consumption in sequentially induced states ''L'' and ''E'' of respiration. The ''L/E'' ratio is an index of [[uncoupling]] or [[dyscoupling]] at constant ETS capacity. ''L/E'' increases with uncoupling from a theoretical minimum of 0.0 for a fully coupled system, to 1.0 for a fully uncoupled ([[non-coupled]]) system. | ||
|info=[[MiPNet12.15]]; [[Gnaiger_2009_IJBCB]]; [[List of respiratory states]] | |info=[[MiPNet12.15]]; [[Gnaiger_2009_IJBCB]]; [[List of respiratory states]] | ||
|type=Respiration | |type=Respiration |
Revision as of 18:00, 28 February 2011
Description
The LEAK control ratio, L/E, is the flux ratio of LEAK respiration over ETS capacity, as determined by measurement of oxygen consumption in sequentially induced states L and E of respiration. The L/E ratio is an index of uncoupling or dyscoupling at constant ETS capacity. L/E increases with uncoupling from a theoretical minimum of 0.0 for a fully coupled system, to 1.0 for a fully uncoupled (non-coupled) system.
Abbreviation: L/E
Reference: MiPNet12.15; Gnaiger_2009_IJBCB; List of respiratory states
Labels:
Regulation: Respiratory state"Respiratory state" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Flux Control; Additivity; Threshold; Excess Capacity"Flux Control; Additivity; Threshold; Excess Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Coupling; Membrane Potential"Coupling; Membrane Potential" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.