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| {{MitoPedia
| | #REDIRECT [[LEAK respiration]] |
| |abbr=''L''
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| |description=The '''LEAK state''', ''L'', is the non-phosphorylating resting state of intrinsic [[uncoupled]] or [[Dyscoupled respiration|dyscoupled respiration]] when oxygen flux is maintained mainly to compensate for the [[proton leak]] when ATP synthase is not active.
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| *[[LEAK state with ATP]]: ''L''<sub>T</sub>
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| *[[LEAK state with Omy]]: ''L''<sub>Omy</sub>
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| *[[LEAK state without adenylates]]: ''L''<sub>N</sub>
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| |info=[[MiPNet12.15]]; [[List of respiratory states]]
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| |type=Respiration
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| }}
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| {{MitoPedia topics
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| |mitopedia topic=Respiratory state
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| |type=Respiration
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| }}
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| ==LEAK==
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| * Not [[State 2]] in the classical sense, but frequently called 'State 2', State 4, State 4o, basal state, or inactive state of respiration.
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| Respiration compensating for the [[proton leak]] is the main component of [[LEAK respiration]]. If proton leak were the only component involved, it would make sense to simply write leak respiration for the compensatory oxygen flux. Proton slip and cation cycling, however, are also involved to a larger or smaller extent to stimulate LEAK respiration. The upper case 'LEAK', therefore, should make us aware that this is more accurately considered as an acronym, and cannot be taken as a definitive delineation of the stimulatory mechanism in the LEAK state of respiration.
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